Anti-Shank2 Antibody (N23B/6)
Primary Antibody
Human, Mouse, Rat
N23B/6
IHC, IP, WB
Mouse
Purified
Shank2 Cortbp1
160 kDa
![Immunoblots on brain membranes prepared from whole rat (RBM) and mouse (MBM) brain, and from human cerebral cortex [HBM(Cx)] and hippocampus [HBM(H)].](http://cdn.shopify.com/s/files/1/0014/8806/0475/products/validation-image-73-088-n23b-6-wb-2_{width}x.jpg?v=1626904249)
Adult rat hippocampus immunohistochemistry.
![Immunoblots on brain membranes prepared from whole rat (RBM) and mouse (MBM) brain, and from human cerebral cortex [HBM(Cx)] and hippocampus [HBM(H)].](http://cdn.shopify.com/s/files/1/0014/8806/0475/products/validation-image-73-088-n23b-6-wb-2_1024x.jpg?v=1626904249)
- MacGillavry HD, Kerr JM, Kassner J, Frost NA, Blanpied TA. (2016), 'Shank-cortactin interactions control actin dynamics to maintain flexibility of neuronal spines and synapses..' European Journal of Neuroscience. 10.1111/ejn.13129.
- Tao-Cheng JH, Azzam R, Crocker V, Winters CA, Reese T. (2015), 'Depolarization of Hippocampal Neurons Induces Formation of Nonsynaptic NMDA Receptor Islands Resembling Nascent Postsynaptic Densities..' eNeuro. 10.1523/ENEURO.0066-15.2015.
- Farley MM, Swulius MT, Waxham MN. (2015), 'Electron tomographic structure and protein composition of isolated rat cerebellar, hippocampal and cortical postsynaptic densities..' Neuroscience. 10.1016/j.neuroscience.2015.07.062.
- Schneider K, Seemann E, Liebmann L, Ahuja R, Koch D, Westermann M, Hübner CA, Kessels MM, Qualmann B. (2014), 'ProSAP1 and membrane nanodomain-associated syndapin I promote postsynapse formation and function..' The Journal of Biology. 10.1083/jcb.201307088.
- Han K, Holder JL Jr, Schaaf CP, Lu H, Chen H, Kang H, Tang J, Wu Z, Hao S, Cheung SW, Yu P, Sun H, Breman AM, Patel A, Lu HC, Zoghbi HY. (2013), 'SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties..' Nature. 10.1038/nature12630.
- Qian H, Matt L, Zhang M, Nguyen M, Patriarchi T, Koval OM, Anderson ME, He K, Lee HK, Hell JW. (2012), 'β2-Adrenergic receptor supports prolonged theta tetanus-induced LTP..' Journal of Neurophysiology. 10.1152/jn.00374.2011.
- Verpelli C, Dvoretskova E, Vicidomini C, Rossi F, Chiappalone M, Schoen M, Di Stefano B, Mantegazza R, Broccoli V, Böckers TM, Dityatev A, Sala C. (2011), 'Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses..' The Journal of Biological Chemistry. 10.1074/jbc.M111.258384.
- Braude JP, Vijayakumar S, Baumgarner K, Laurine R, Jones TA, Jones SM, Pyott SJ. (), 'Deletion of Shank1 has minimal effects on the molecular composition and function of glutamatergic afferent postsynapses in the mouse inner ear..' Hearing Research. 10.1016/j.heares.2015.01.008.
- Peykov S, Berkel S, Schoen M, Weiss K, Degenhardt F, Strohmaier J, Weiss B, Proepper C, Schratt G, Nöthen MM, Boeckers TM, Rietschel M, Rappold GA. (), 'Identification and functional characterization of rare SHANK2 variants in schizophrenia..' Molecular Psychiatry. 10.1038/mp.2014.172.
- Baple EL, Maroofian R, Chioza BA, Izadi M, Cross HE, Al-Turki S, Barwick K, Skrzypiec A, Pawlak R, Wagner K, Coblentz R, Zainy T, Patton MA, Mansour S, Rich P, Qualmann B, Hurles ME, Kessels MM, Crosby AH. (), 'Mutations in KPTN cause macrocephaly, neurodevelopmental delay, and seizures..' Am J Human Genetics. 10.1016/j.ajhg.2013.10.001.
- Berkel S, Tang W, Treviño M, Vogt M, Obenhaus HA, Gass P, Scherer SW, Sprengel R, Schratt G, Rappold GA. (), 'Inherited and de novo SHANK2 variants associated with autism spectrum disorder impair neuronal morphogenesis and physiology..' Human Molecular Genetics. 10.1093/hmg/ddr470.
- Xie M, Rich TC, Scheitrum C, Conti M, Richter W. (), 'Inactivation of multidrug resistance proteins disrupts both cellular extrusion and intracellular degradation of cAMP..' Molecular Pharmacology. 10.1124/mol.111.071134.
- Tao-Cheng JH, Dosemeci A, Gallant PE, Smith C, Reese T. (), 'Activity induced changes in the distribution of Shanks at hippocampal synapses..' Neuroscience. 10.1016/j.neuroscience.2010.03.041.