Anti-SAPAP1 Antibody (N238/30)

Name: Anti-SAPAP1 Antibody
Brand: NeuroMab
SKU: 75-468
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

N238/30

Applications

ICC, IHC

Host Species

Mouse

Format

Purified

Gene Name

DLGAP1 DAP1 GKAP

Molecular Weight

110 kDa (varies due to post-translational modifications)

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Adult rat hippocampus (top), thalamus (bottom left) and superior colliculus (bottom right) immunohistochemistry with antigen retrieval via pepsin pretreatment.

Volume: 100 µL

Variant

Price:

$308

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Product Details

Target

Disks large-associated protein 1 (SAPAP1) SAPAP-1

Target Description

SAPAP1 (also known as disks large associated protein 1, DAP-1, or DLGAP1) is a member of the SAPAP or DLGAP family of proteins. SAPAP1 is part of the scaffold in neuronal cells of the brain and is a component of the postsynaptic complex. SAPAP1 acts as an adaptor protein that binds synaptic scaffold proteins, cytoskeletal proteins and signaling proteins including PSD-95 and SHANK. SAPAP1 is expressed in neurons of the cortex, hippocampus and in Purkinje cells in the cerebellum. Diseases associated with DLGAP1 include Retinitis Pigmentosa 55 and Obsessive-Compulsive Disorder

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N238/30

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

DLGAP1 DAP1 GKAP

Molecular Weight

110 kDa (varies due to post-translational modifications)

Antigen

Fusion protein amino acids 772-992 (C-terminus) of rat SAPAP1 (also known as disks largeassociated protein 1, DAP-1, guanylate kinase-associated protein, GKAP, SAP90/PSD-95-associated/binding protein 1 and Dlgap1, accession number P97836); Mouse: 99% identity (200/201 amino acids identical) Human: 99% identity (199/201 amino acids identical) 55-65% identity with other SAPAPs

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2722668

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected immunoperoxidase-diaminobenzidine / immunofluorescence staining pattern when used to stain brain sections.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Disks large-associated protein 1 (SAPAP1) SAPAP-1

UniProt Details

UniProt (Human): O14490
UniProt (Immunogen Species): P97836

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Anti-SAPAP1 Antibody (N238/30)

Anti-SAPAP1 Antibody
SKU: 75-468

Bulk Order Anti-SAPAP1 Antibody

Product Details

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Anti-SAPAP1 Antibody (N238/30)

Anti-SAPAP1 Antibody SKU: 75-468

Bulk Order Anti-SAPAP1 Antibody

Product Details

Anti-SAPAP1 Antibody
SKU: 75-468