Anti-S100A5 Antibody (N176/35)

Name: Anti-S100A5 Antibody
Brand: NeuroMab
SKU: 75-199
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet KO Validated

Product Type

Primary Antibody

Species Reactivity

Mouse, Rat

Clone

N176/35

Applications

ICC, WB

Host Species

Mouse

Format

Purified

Gene Name

S100a5 S100d

Molecular Weight

10 kDa

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Immunoblot versus adult rat brain membranes (RBM) and whole brain homogenates from S100A5-tauGFP (targeted deletion of S100A5 and replaced with coding region of tau fused to GFP) heterozygote (Het) and KO mice and probed with N176A/35 TC supe (left) and rabbit anti-S100A5 antibody (right). Samples courtesy of Tim McClintock, University of Kentucky.

Volume: 100 µL

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Product Details

Target

S100A5

Target Description

Protein S100A5 is encoded by the gene S100A5 and a member of the S100 family of proteins. S100A5 is a calcium-binding cytosolic proteins and is also a member of the damage-associated molecular pattern molecules (DAMPs) family, a group of proteins that are released from the extracellular or intracellular space following tissue injury or cell death. S100A5 is localized in the cytoplasm and implicated in the regulation of a number of cellular processes such as cell cycle progression and extracellular signal transduction. S100A5 has been found in brain and kidney. Diseases associated with this gene include Astrocytoma.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N176/35

Isotype

IgG1

Applications

ICC, WB

Host Species

Mouse

Gene Name

S100a5 S100d

Molecular Weight

10 kDa

Antigen

Fusion protein amino acids 1-93 (full-length) of rat S100A (also known as S100 calcium-binding protein A5 and S-100D, accession number P63083); Mouse: 100% identity (93/93 amino acids identical); Human: 93% identity (87/93 amino acids identical); ~50% identity with S100A4 and S100A6

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2315917

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

Does not cross-react with S100A4 or S100A6 (based on KO validation results)

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Protein S100-A5 (Protein S-100D) (S100 calcium-binding protein A5)

UniProt Details

UniProt (Human): P33763

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Anti-S100A5 Antibody (N176/35)

Anti-S100A5 Antibody
SKU: 75-199

Bulk Order Anti-S100A5 Antibody

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Anti-S100A5 Antibody (N176/35)

Anti-S100A5 Antibody SKU: 75-199

Bulk Order Anti-S100A5 Antibody

Product Details

Anti-S100A5 Antibody
SKU: 75-199