RNA-Binding Motif Protein 17 or Splicing factor 45 is encoded by the gene RBM17. RBM17 is a component of the spliceosome complex and displays catalytic activity during mRNA splicing. RBM17 is involved in alternative splicing, resulting in different isoforms of a gene. RBM is also thought to play a role in DNA repair (Red: Chaouki et al 2006) RBM17 is widely expressed in the nucleus and important for development. Diseases associated with this gene include sickle cell anemia and forms of Ataxia 1.
ICC, IHC, WB
Fusion protein amino acids 100-200 of human RBM17 (also known as RNA-binding motif protein 17, Splicing factor 45, 45 kDa-splicing factor, SPF45, accession number Q96I25); Mouse: 99% identity (100/101 amino acids identical); Rat: 99% identity (100/101 amino acids identical)
Human, Mouse, Rat
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
No cross-reactivity reported
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from opening
Splicing factor 45 (45 kDa-splicing factor) (RNA-binding motif protein 17)