Anti-PICK1 Antibody (L20/8)

Name: Anti-PICK1 Antibody
Brand: NeuroMab
SKU: 75-040
Price: 285.0 USD
Availability: InStock

from NeuroMab Datasheet KO Validated

filler

Clonality

Monoclonal

Applications

IHC, IP, WB

Host Species

Mouse

Gene Name

PICK1 PRKCABP

Molecular Weight

45 kDa

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Adult rat hippocampus immunohistochemistry.

$Immunoblot against crude membrane fractions from whole mouse (MBM) or rat (RBM) brain and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)] or cerebellum [HBM(Cb)] and probed with L20/8 (left) or N52A/42 (right) TC supe.$

$Immunoblot against membrane fractions from adult rat brain (RBM) and hippocampi (MHM) from wild-type (WT) and PICK1 knockout (KO) mice probed with L20/8 TC supe. Mouse samples courtesy of Richard Huganir (Johns Hopkins University, HHMI).$

Adult rat hippocampus immunohistochemistry.

Product Details

Target

PICK1

Target Description

PRKCA-binding protein or PICK1 scaffold is encoded by the gene PICK1. PICK1 is a scaffold protein which acts as an adaptor protein that binds and organizes the location of membrane proteins. Functions to cluster receptors and plays a role in synaptic plasticity. PICK1 is ubiguitously expressed and found in high levels in brain and testis. Cellularly, PICK1 is found at perinuclear region, mitochondria and synapses. Diseases associated with PICK1 include Spermatogenic Failure and Depression.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

L20/8

Isotype

IgG2a

Applications

IHC, IP, WB

Host Species

Mouse

Gene Name

PICK1 PRKCABP

Molecular Weight

45 kDa

Antigen

Fusion protein amino acids 10-130 of rat PICK1 (accession number AAG48152); Human: 100% identity (121/121 amino acids); Mouse=99% identity (120/121 amino acids)

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2164544

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein)

UniProt Details

UniProt (Human): Q9NRD5
UniProt (Immunogen Species): Q9NRD5

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Anti-PICK1 Antibody (L20/8)

Anti-PICK1 Antibody
SKU: 75-040

Product Details

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Anti-PICK1 Antibody (L20/8)

Anti-PICK1 Antibody SKU: 75-040

Product Details

Anti-PICK1 Antibody
SKU: 75-040