PRKCA-binding protein or PICK1 scaffold is encoded by the gene PICK1. PICK1 is a scaffold protein which acts as an adaptor protein that binds and organizes the location of membrane proteins. Functions to cluster receptors and plays a role in synaptic plasticity. PICK1 is ubiguitously expressed and found in high levels in brain and testis. Cellularly, PICK1 is found at perinuclear region, mitochondria and synapses. Diseases associated with PICK1 include Spermatogenic Failure and Depression.
IHC, IP, WB
Fusion protein amino acids 10-130 of rat PICK1 (accession number AAG48152); Human: 100% identity (121/121 amino acids); Mouse=99% identity (120/121 amino acids)
Human, Mouse, Rat
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
No cross-reactivity reported
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from opening
PRKCA-binding protein (Protein interacting with C kinase 1) (Protein kinase C-alpha-binding protein)