Anti-PICK1 Antibody (L20/8)


Primary Antibody
Human, Mouse, Rat
L20/8
ICC, IHC, IP, WB
Mouse
Purified
PICK1 PRKCABP
45 kDa

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Anti-PICK1 Antibody
SKU: 75-040

Volume: 100 µL
Price:
Sale price$308


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Product Specific References for Applications and Species

Immunocytochemistry: Mouse
PMID Dilution Publication
345002851:100Wang, L., et al. 2021. The PICK1/TLR4 complex on microglia is involved in the regulation of LPS-induced sepsis-associated encephalopathy. International immunopharmacology, 108116.
Immunocytochemistry: Rat
PMID Dilution Publication
23918399not listedAnggono, V., et al. 2013. PICK1 interacts with PACSIN to regulate AMPA receptor internalization and cerebellar long-term depression.. PNAS: USA, 13976-13981.
22915106not listedJaafari, N., et al. 2012. PICK1 mediates transient synaptic expression of GluA2-lacking AMPA receptors during glycine-induced AMPA receptor trafficking.. Journal of Neuroscience, 11618-11630.
21252856not listedNakamura, Y., et al. 2011. PICK1 inhibition of the Arp2/3 complex controls dendritic spine size and synaptic plasticity.. The EMBO Journal, 719-730.
Immunohistochemistry: Human
PMID Dilution Publication
336601481:100Zhou, Y., et al. 2021. Protein interacting with C-kinase 1 is involved in epithelial-mesenchymal transformation and suppresses progress of gastric cancer. Medical Oncology, 34.
Immunohistochemistry: Mouse
PMID Dilution Publication
346731361:100Mo, Y., et al. 2021. Electroacupuncture prevents LPS- induced neuroinflammation via upregulation of PICK-TLR4 complexes in the microglia of hippocampus. Brain research bulletin, 295-304.
345002851:100Wang, L., et al. 2021. The PICK1/TLR4 complex on microglia is involved in the regulation of LPS-induced sepsis-associated encephalopathy. International immunopharmacology, 108116.
Immunoprecipitation: Mouse
PMID Dilution Publication
334886942ugGu, Y., et al. 2020. Electroacupuncture Attenuates CFA-Induced Inflammatory Pain by Regulating CaMKII. Neural Plasticity, 8861994.
265667952-4ugZhu, J., et al. 2016. Protein Interacting C-Kinase 1 Modulates Surface Expression of P2Y6 Purinoreceptor, Actin Polymerization and Phagocytosis in Microglia.. Neurochemical Research, 795-803.
259047942-4ug/mlWang, Y.N., et al. 2015. Protein Interacting with C-Kinase 1 Deficiency Impairs Glutathione Synthesis and Increases Oxidative Stress via Reduction of Surface Excitatory Amino Acid Carrier 1.. Journal of Neuroscience, 6429-6443.
21496646not listedZhang, J., et al. 2011. The AAA+ ATPase Thorase regulates AMPA receptor-dependent synaptic plasticity and behavior.. Cell, 284-299.
Immunoprecipitation: Rat
PMID Dilution Publication
289515545ugGol, S., et al. 2017. Endocytosis and lysosomal degradation of GluA2/3 AMPARs in response to oxygen/glucose deprivation in hippocampal but not cortical neurons. Scientific Reports, 12318.
28855251not listedFiuza, M., et al. 2017. PICK1 regulates AMPA receptor endocytosis via direct interactions with AP2 α-appendage and dynamin. . Journal of Cell Biology, 3323-3338.
28404816not listedRajgor, D., et al. 2017. The PICK1 Ca2+ sensor modulates N-methyl-d-aspartate (NMDA) receptor-dependent microRNA-mediated translational repression in neurons.. Journal of Biological Chemistry, 9774-9786.
254756872ugRocca, D.L., et al. 2015. PICK1 links AMPA receptor stimulation to Cdc42.. Neuroscience Letters, 155-159.
182970633ugRocca, D.L., et al. 2008. Inhibition of Arp2/3-mediated actin polymerization by PICK1 regulates neuronal morphology and AMPA receptor endocytosis.. Nature Cell Biology, 259-271.
Western Blot: Feline
PMID Dilution Publication
256687721:200Williams, K., et al. 2015. Experience-dependent central vision deficits: Neurobiology and visual acuity.. Vision Research, 68-78.
Western Blot: Human
PMID Dilution Publication
32531799not listedChen, L., et al. 2020. Islet-cell autoantigen 69 accelerates liver regeneration by downregulating Tgfbr1 and attenuating Tgfβ signaling in mice. FEBS Letters, 2881-2893.
26466675not listedCockbill, L.M., et al. 2015. Protein interacting with C kinase 1 suppresses invasion and anchorage-independent growth of astrocytic tumor cells.. Molecular Biology of the Cell, 4552-4561.
Western Blot: Mouse
PMID Dilution Publication
346731361:5000Mo, Y., et al. 2021. Electroacupuncture prevents LPS- induced neuroinflammation via upregulation of PICK-TLR4 complexes in the microglia of hippocampus. Brain research bulletin, 295-304.
345002851:5000Wang, L., et al. 2021. The PICK1/TLR4 complex on microglia is involved in the regulation of LPS-induced sepsis-associated encephalopathy. International immunopharmacology, 108116.
344555391:1000Longatti, A., et al. 2021. Arhgap22 Disruption Leads to RAC1 Hyperactivity Affecting Hippocampal Glutamatergic Synapses and Cognition in Mice. Molecular Neurobiology, 6092-6110.
341100731:2000Wickens, M.M., et al. 2021. Sex-specific role for prefrontal cortical protein interacting with C kinase 1 in cue-induced cocaine seeking. Addiction Biology, e13051.
321477341:1000Koch, N., et al. 2020. Syndapin I Loss-of-Function in Mice Leads to Schizophrenia-Like Symptoms. Cerebral Cortex, 4306-4324.
315030671:2000Faccidomo, S., et al. 2020. Pharmacological inhibition of glycogen synthase kinase 3 increases operant alcohol self-administration in a manner associated with altered pGSK-3β, protein interacting with C kinase and GluA2 protein expression in the reward pathway of male C57BL/6J mice. Behavioral Pharmacology, 15-26.
30699097not listedHan, K., et al. 2019. Islet-cell autoantigen 69 mediates the antihyperalgesic effects of electroacupuncture on inflammatory pain by regulating spinal glutamate receptor subunit 2 phosphorylation through protein interacting with C-kinase 1 in mice. Pain, 712-723.
30402043not listedMo, Y., et al. 2018. PICK1 Deficiency Induces Autophagy Dysfunction via Lysosomal Impairment and Amplifies Sepsis-Induced Acute Lung Injury. Mediators of Inflammation, 6757368.
294711071:10,000Qian, M., et al. 2018. PICK1 deficiency exacerbates sepsis-associated acute lung injury and impairs glutathione synthesis via reduction of xCT. . Free Radical Biology and Medicine, 23-34.
27800545not listedChenaux, G., et al. 2016. Loss of SynDIG1 Reduces Excitatory Synapse Maturation But Not Formation In Vivo. eNeuro, .
268345561:1000Folci, A., et al. 2016. Myosin IXa Binds AMPAR and Regulates Synaptic Structure, LTP, and Cognitive Function. Frontiers in Molecular Neuroscience, 1.
265667951:2000Zhu, J., et al. 2016. Protein Interacting C-Kinase 1 Modulates Surface Expression of P2Y6 Purinoreceptor, Actin Polymerization and Phagocytosis in Microglia.. Neurochemical Research, 795-803.
26306493not listedHe, J., et al. 2015. ICA1L forms BAR-domain complexes with PICK1 and is crucial for acrosome formation in spermiogenesis.. Journal of Cell Science, 3822-3836.
260058511:1000Shin, S., et al. 2015. mGluR5 in the nucleus accumbens is critical for promoting resilience to chronic stress. Nature Neuroscience, 1017-1024.
255594031:2500Pandey, S.P., et al. 2015. Development- and age-related alterations in the expression of AMPA receptor subunit GluR2 and its trafficking proteins in the hippocampus of male mouse brain.. Biogerontology, 317-328.
255474631:1000Li, Q.J., et al. 2015. Loss of ICA69 potentiates long-lasting hyperalgesia after subcutaneous formalin injection into the mouse hindpaw.. Neurochemical Research, 579-590.
24069373not listedBreiderhoff, T., et al. 2013. Sortilin-related receptor SORCS3 is a postsynaptic modulator of synaptic depression and fear extinction. PLoS One, e75006.
237198051 : 1000Hoy, J.L., et al. 2013. Neuroligin1 drives synaptic and behavioral maturation through intracellular interactions.. Journal of Neuroscience, 9364-9384.
23630453not listedCao, M., et al. 2013. PICK1 and ICA69 control insulin granule trafficking and their deficiencies lead to impaired glucose tolerance. PLoS Biology, e1001541.
223692341:500Wilke, S.A., et al. 2012. NeuroD2 regulates the development of hippocampal mossy fiber synapses.. Neural Development, 9.
194831941:1000Labrie, V., et al. 2009. Serine racemase is associated with schizophrenia susceptibility in humans and in a mouse model.. Human Molecular Genetics, 3227-3243.
Western Blot: Rat
PMID Dilution Publication
35721319not listedStan, G.F., et al. 2022. Ca 2+ Regulates Dimerization of the BAR Domain Protein PICK1 and Consequent Membrane Curvature. Frontiers in Molecular Neuroscience, 893739.
28855251not listedFiuza, M., et al. 2017. PICK1 regulates AMPA receptor endocytosis via direct interactions with AP2 α-appendage and dynamin. . Journal of Cell Biology, 3323-3338.
284048161:500Rajgor, D., et al. 2017. The PICK1 Ca2+ sensor modulates N-methyl-d-aspartate (NMDA) receptor-dependent microRNA-mediated translational repression in neurons.. Journal of Biological Chemistry, 9774-9786.
277937711:1000Farooq, M., et al. 2017. Lithium increases synaptic GluA2 in hippocampal neurons by elevating the δ-catenin protein. Neuropharmacology, 426-433.
243583151:2000Wang, Z., et al. 2013. C-terminal domain of ICA69 interacts with PICK1 and acts on trafficking of PICK1-PKCα complex and cerebellar plasticity.. PLoS One, e83862.
238436141:1000Murk, K., et al. 2013. The antagonistic modulation of Arp2/3 activity by N-WASP, WAVE2 and PICK1 defines dynamic changes in astrocyte morphology. Journal of Cell Science, 3873-3883.
22915106not listedJaafari, N., et al. 2012. PICK1 mediates transient synaptic expression of GluA2-lacking AMPA receptors during glycine-induced AMPA receptor trafficking.. Journal of Neuroscience, 11618-11630.
226239121:200Murphy, K.M., et al. 2012. Cortical development of AMPA receptor trafficking proteins.. Frontiers in Molecular Neuroscience, 65.
218550551:3000Ghasemzadeh, M.B., et al. 2011. Glutamatergic plasticity in medial prefrontal cortex and ventral tegmental area following extended-access cocaine self-administration.. Brain Research, 60-71.
21291912not listedHadlock, G.C., et al. 2011. Ex vivo identification of protein-protein interactions involving the dopamine transporter.. Journal of Neuroscience Methods, 303-307.
21252856not listedNakamura, Y., et al. 2011. PICK1 inhibition of the Arp2/3 complex controls dendritic spine size and synaptic plasticity.. The EMBO Journal, 719-730.
20802490not listedEvers, D.M., et al. 2010. Plk2 attachment to NSF induces homeostatic removal of GluA2 during chronic overexcitation.. Nature Neuroscience, 1199-1207.
20403402not listedShao, X., et al. 2010. Threonine 82 at the PDZ domain of PICK1 is critical for AMPA receptor interaction and localization.. Neurochemistry International, 962-970.
193688201:3000Ghasemzadeh, M.B., et al. 2009. Region-specific alterations in glutamate receptor expression and subcellular distribution following extinction of cocaine self-administration.. Brain Research, 89-102.
191354701:3000Ghasemzadeh, M.B., et al. 2009. Locomotor sensitization to cocaine is associated with distinct pattern of glutamate receptor trafficking to the postsynaptic density in prefrontal cortex: early versus late withdrawal effects.. Pharmacology Biochemistry Behavior, 383-392.
191059751:300Ghasemzadeh, M.B., et al. 2009. Behavioral sensitization to cocaine is associated with increased glutamate receptor trafficking to the postsynaptic density after extended withdrawal period.. Neuroscience, 414-426.

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