Anti-Pan-QKI Antibody (N147/6)

Name: Anti-Pan-QKI Antibody
Brand: NeuroMab
SKU: 75-168
Price: 285.0 USD
Availability: InStock

from NeuroMab Datasheet

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Clonality

Monoclonal

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Qki Qk QKI HKQ Qk1 Qka1

Molecular Weight

36-38 kDa

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Immunoblots on membranes prepared from whole mouse (MBM) and rat (RBM) brain, and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)], and cerebellum [HBM(Cb)].

Adult rat hippocampus immunohistochemistry (high and low magnification).

Adult rat brain membrane (RBM) and transfected cell immunoblot: extracts of RBM and COS cells transiently transfected with Flag-tagged QKI-5, QKI-6, QKI-7 and QKI-7b or untagged Kv2.1 plasmids and probed with N147/6 (left) and mouse anti-Flag (right).

Immunoblots on membranes prepared from whole mouse (MBM) and rat (RBM) brain, and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)], and cerebellum [HBM(Cb)].

Product Details

Target

Pan-QKI

Target Description

QKI5, QKI6, QKI7 and QKI7b are alternatively spliced mRNAs from the QKI1 gene. The proteins are RNA-binding and have roles in the regulation of splicing, export and stability of mRNA. They are involved in myelinization.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N147/6

Isotype

IgG2b

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Qki Qk QKI HKQ Qk1 Qka1

Molecular Weight

36-38 kDa

Antigen

Fusion protein amino acids 1-341 (full-length) of human QKI-5 (also known as Protein quaking, HqkI and Hqk, accession number Q96PU8); Mouse: 100% identity (341/341 amino acids identical); Rat: 99% identity (339/341 amino acids identical); Greater than 90% identity with QKI-6, QKI-7 and QKI-7b

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2173149

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

Cross-reacts with QKI-6, QKI-7 and QKI-7b

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

QKI-5, QKI-6, QKI-7 and QKI-7b Protein quaking (RqkI) Protein quaking (Hqk) (HqkI) Protein quaking (MqkI) (qkI)

UniProt Details

UniProt (Human): Q96PU8

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Anti-Pan-QKI Antibody (N147/6)

Anti-Pan-QKI Antibody
SKU: 75-168

Product Details

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Anti-Pan-QKI Antibody (N147/6)

Anti-Pan-QKI Antibody SKU: 75-168

Product Details

Anti-Pan-QKI Antibody
SKU: 75-168