Adult rat brain membrane (RBM) and transfected cell immunoblot: extracts of RBM and COS cells transiently transfected with Myc-tagged NGL-1, NGL-2 NGL-3 or untagged Kv2.1 plasmid and probed with N51/6 (left) or K89/41 (right) TC supe.
Leucine Rich Repeat Containing 4B is encoded by the gene LRRC4B. LRRC4B is a synaptic adhesion protein that regulates the formation of excitatory synapses. The trans-synaptic adhesion between LRRC4B and PTPRF regulates the formation of excitatory synapses in a bidirectional manner. LRRC4B is expressed in the brain. No disorders were found to be associated with LRRC4B.
ICC, IP, WB
Fusion protein amino acids 598-709 of rat NGL-3 (Leucine-rich repeat-containing 4B protein (Lrrc4B), accession number XP_218615); Mouse: 100% identity (112/112 amino acids identical); Human: 94% identity (105/112 amino acids identical)
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
No cross-reactivity against NGL-1 or NGL-2
Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from opening
Leucine-rich repeat-containing protein 4B (Netrin-G3 ligand) (NGL-3)