Our Anti-Nav1.7 Na+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N68/6. It detects human, mouse, and rat Nav1.7 Na+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
Nav1.7 Na+ channel
Nav1.7 subunit alpha, or SCN9A, is a member of the voltage gated sodium channel family. It is expressed at the terminal ends of sensory neurons in the dorsal root ganglion (DRG) and in trigeminal and sympathetic ganglion neurons. A major function of Nav1.7 is the generation and conduction of action potentials in nociceptors, or “pain receptors” and thus involved in pain sensation. Changes in Nav1.7 expression have been linked to primary erythermalgia, primary erythermalgia, and Congenital insensitivity to pain
Purified by Protein A chromatography
Fusion protein amino acids 1751-1946 (cytoplasmic C-terminus) of human Nav1.7 (accession number Q15858) produced recombinantly in E. Coli
Human, Mouse, Rat
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL650 Ex: 655 nm, Em: 676 nm
No cross-reactivity against other Nav channels
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
12 months from date of receipt
Shipped on ice packs
Sodium channel protein type 9 subunit alpha (Neuroendocrine sodium channel) (hNE-Na) (Peripheral sodium channel 1) (PN1) (Sodium channel protein type IX subunit alpha) (Voltage-gated sodium channel subunit alpha Nav1.7)