Anti-MPP8 Antibody (N119/44)

Name: Anti-MPP8 Antibody
Brand: NeuroMab
SKU: 75-154
Price: 285.0 USD
Availability: InStock

from NeuroMab Datasheet

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Clonality

Monoclonal

Applications

ICC, WB

Host Species

Mouse

Gene Name

MPHOSPH8 MPP8

Molecular Weight

100 kDa

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Transfected cell immunofluorescence: COS cells expressing GFP-tagged human MPP8. Red = N119/44, Green = GFP, Blue = Hoechst nuclear stain.

Transfected cell immunoblot: extracts of COS cells transfected with GFP-tagged MPP8 and untagged Kv2.1 plasmids and probed with N119/44 (left panel) and K89/34 (right panel) TC supe.

Product Details

Target

MPP8

Target Description

M-Phase Phosphoprotein 8 is encoded by the gene MPHOSPH8. MPHOSPH8 is a heterochromatin component that specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic repression. MPHOSPH8 is expressed in the brain. Diseases associated with MPHOSPH8 include Charcot-Marie-Tooth Disease.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N119/44

Isotype

IgG2b

Applications

ICC, WB

Host Species

Mouse

Gene Name

MPHOSPH8 MPP8

Molecular Weight

100 kDa

Antigen

Fusion protein amino acids 50-120 (Chromo domain) of human MPP8 (also known as m-phase phosphoprotein 8 and MPHOSPH8, accession number Q99549); Rat: 92% identity (66/71 amino acids identical); Mouse: 91% identity (65/71 amino acids identical)

Species Reactivity

Human

Antibody Registry ID

AB_2146181

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

M-phase phosphoprotein 8 (Two hybrid-associated protein 3 with RanBPM) (Twa3)

UniProt Details

UniProt (Human): Q99549
UniProt (Immunogen Species): Q99549

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Anti-MPP8 Antibody (N119/44)

Anti-MPP8 Antibody
SKU: 75-154

Product Details

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Anti-MPP8 Antibody (N119/44)

Anti-MPP8 Antibody SKU: 75-154

Product Details

Anti-MPP8 Antibody
SKU: 75-154