Anti-MMP9 Antibody (L51/82)

Name: Anti-MMP9 Antibody
Brand: NeuroMab
SKU: 75-100
Price: 295.0 USD
Availability: InStock

from NeuroMab Datasheet

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

L51/82

Applications

IHC, IP, WB

Host Species

Mouse

Format

Purified

Gene Name

Mmp9

Molecular Weight

92 and 82 kDa(Pro and Active forms)

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Immunoblot versus lysates of whole rat brain (WBH) and of COS-1 cells transfected with human and rat MMP9 (hMMP9 and rMMP9, respectively) and Kv2.1 plasmids and probed with L51/82 (left), K89/34 (middle) and loading control (right) TC supe.

Adult rat hippocampus immunohistochemistry.

Volume: 100 µL

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Product Details

Target

MMP9

Target Description

Matrix Metallopeptidase 9 is encoded by the gene MMP9. MMP9 is a member of the peptidase M10A family. MMP9 may play a role in local proteolysis of the extracellular matrix, leukocyte migration, and bone osteoclastic resorption. MMP9 cleaves type IV and V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. MMP9 is expressed in neutrophils. Diseases associated with MMP9 include Metaphyseal Anadysplasia 2 and Metaphyseal Anadysplasia.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

L51/82

Isotype

IgG2a

Applications

IHC, IP, WB

Host Species

Mouse

Gene Name

Mmp9

Molecular Weight

92 and 82 kDa(Pro and Active forms)

Antigen

Fusion protein amino acids 1-708 (full-length) of rat MMP9 (also known as matrix metalloproteinase 9, 92 kDa type IV collagenase, 92 kDa gelatinase, gelatinase B and GELB, accession number P50282); Human: 68% identity (482/708 amino acids identical); Mouse: 74% identity (548/731 amino acids identical); Less than 50% identity with MMP2

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2297774

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Matrix metalloproteinase-9 (MMP-9) (EC 3.4.24.35) (92 kDa gelatinase) (92 kDa type IV collagenase) (Gelatinase B) (GELB)

UniProt Details

UniProt (Human): P14780
UniProt (Immunogen Species): P50282

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Anti-MMP9 Antibody (L51/82)

Anti-MMP9 Antibody
SKU: 75-100

Bulk Order Anti-MMP9 Antibody

Product Details

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Anti-MMP9 Antibody (L51/82)

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Anti-MMP9 Antibody
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