Matrix Metallopeptidase 9 is encoded by the gene MMP9. MMP9 is a member of the peptidase M10A family. MMP9 may play a role in local proteolysis of the extracellular matrix, leukocyte migration, and bone osteoclastic resorption. MMP9 cleaves type IV and V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. MMP9 is expressed in neutrophils. Diseases associated with MMP9 include Metaphyseal Anadysplasia 2 and Metaphyseal Anadysplasia.
Purified
1 mg/mL
Monoclonal
L51/82
IgG2a
IHC, IP, WB
Mouse
Mmp9
92 and 82 kDa(Pro and Active forms)
Fusion protein amino acids 1-708 (full-length) of rat MMP9 (also known as matrix metalloproteinase 9, 92 kDa type IV collagenase, 92 kDa gelatinase, gelatinase B and GELB, accession number P50282); Human: 68% identity (482/708 amino acids identical); Mouse: 74% identity (548/731 amino acids identical); Less than 50% identity with MMP2
AB_2297774
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Unconjugated
No cross-reactivity reported
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
24 months from opening
Matrix metalloproteinase-9 (MMP-9) (EC 3.4.24.35) (92 kDa gelatinase) (92 kDa type IV collagenase) (Gelatinase B) (GELB)
