Matrix Metallopeptidase 9 is encoded by the gene MMP9. MMP9 is a member of the peptidase M10A family. MMP9 may play a role in local proteolysis of the extracellular matrix, leukocyte migration, and bone osteoclastic resorption. MMP9 cleaves type IV and V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. MMP9 is expressed in neutrophils. Diseases associated with MMP9 include Metaphyseal Anadysplasia 2 and Metaphyseal Anadysplasia.
IHC, IP, WB
92 and 82 kDa(Pro and Active forms)
Fusion protein amino acids 1-708 (full-length) of rat MMP9 (also known as matrix metalloproteinase 9, 92 kDa type IV collagenase, 92 kDa gelatinase, gelatinase B and GELB, accession number P50282); Human: 68% identity (482/708 amino acids identical); Mouse: 74% identity (548/731 amino acids identical); Less than 50% identity with MMP2
Human, Mouse, Rat
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