Anti-LRP4 (Cytoplasmic) Antibody (N164/6)

Name: Anti-LRP4 (Cytoplasmic) Antibody
Brand: NeuroMab
SKU: 75-182
Price: 319.0 USD
Availability: InStock

1 Citation

Our Anti-LRP4 (cytoplasmic) mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N164/6. It detects mouse and rat LRP4 (cytoplasmic), and is purified by Protein A chromatography. It is great for use in ICC, WB.

Adult rat brain membrane immunoblot.

Species Reactivity

Mouse, Rat

Applications

ICC, WB

Host Species

Mouse

Available Conjugates

490

550

594

650

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Data Sheet

SKU: 75-182

Volume: 100 µL

Variant

Price:

$319.00

Quantity:

Product Details

Target

LRP4 (cytoplasmic)

Target Description

Low-density lipoprotein receptor-related protein 4 or LRP4 is encoded by the gene LRP4. And is a member of the low-density lipoprotein receptor-related protein family. Proteins in this family function in a wide range of physiological processes, including the regulation of lipid metabolism, protection against atherosclerosis, neurodevelopment. LRP4 may be involved in the negative regulation of the canonical Wnt signaling pathway. LRP4 is expressed in bone and several regions of the brain. Mutations in this gene are associated with Cenani-Lenz syndrome.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N164/6

Isotype

IgG1

Applications

ICC, WB

Host Species

Mouse

Gene Name

Lrp4 Kiaa0816

Molecular Weight

215 kDa

Antigen

Fusion protein amino acids 1747-1905 (cytoplasmic C-terminus) of mouse LRP4 (accession number Q8VI56) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2139028

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.110

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Low-density lipoprotein receptor-related protein 4 (LRP-4) (LDLR dan)

UniProt Details

UniProt (Human): O75096
UniProt (Immunogen Species): Q8VI56

Product Specific References for Applications and Species

Western Blot: Mouse

Western Blot: Mouse
PMID	Dilution	Publication
34090516	1:500	Jing, H., et al. . Synapse-specific Lrp4 mRNA enrichment requires Lrp4/MuSK signaling, muscle activity and Wnt non-canonical pathway. Cell Bioscience, 105.

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Anti-LRP4 (Cytoplasmic) Antibody (N164/6)

SKU: 75-182

Product Details

Product Specific References for Applications and Species

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