Low-density lipoprotein receptor-related protein 4 or LRP4 is encoded by the gene LRP4. And is a member of the low-density lipoprotein receptor-related protein family. Proteins in this family function in a wide range of physiological processes, including the regulation of lipid metabolism, protection against atherosclerosis, neurodevelopment. LRP4 may be involved in the negative regulation of the canonical Wnt signaling pathway. LRP4 is expressed in bone and several regions of the brain. Mutations in this gene are associated with Cenani-Lenz syndrome.
Purified by Protein A chromatography
Fusion protein amino acids 1747-1905 (cytoplasmic C-terminus) of mouse LRP4 (accession number Q8VI56) produced recombinantly in E. Coli
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.110
No cross-reactivity reported
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from date of receipt
Shipped on ice packs
Low-density lipoprotein receptor-related protein 4 (LRP-4) (LDLR dan)