Our Anti-Kv1.7 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N471/27. It detects mouse Kv1.7, and is purified by Protein A chromatography. It is great for use in ICC, WB.
Immunoblot against extracts of COS cells transiently transfected with Myc/Flag-tagged Kv1.7 or untagged Kv2.1 plasmid probed with N471/27 (left) or rabbit anti-Flag (right)..
Potassium Voltage-Gated Channel Subfamily A Member 7 or Kv1.7 potassium channel is encoded by the gene KCNA7. Kv1.7 is a potassium channel subunit is a member of the potassium channel, voltage-gated, shaker-related subfamily. Potassium channels form homotetrameric and heterotetrameric channels in the membrane with various other related proteins, including KCNA2, KCNA4, KCNA5, KCNA6, KCNA7. Kv1.7 is detected in heart, skeletal muscle, kidney, brain, and pancreatic islet cells.
Purified by Protein A chromatography
Fusion protein amino acids 1-44 (cytoplasmic N-terminus) and 450-480 (cytoplasmic C-terminus) of mouse Kv1.7 (accession number Q17ST2) produced recombinantly in E. Coli
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
No cross-reactivity reported
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from date of receipt
Shipped on ice packs
Kv1.7 (Potassium voltage-gated channel subfamily A member 7) (Voltage-gated potassium channel subunit Kv1.7)