Anti-Homer1L Antibody (L113/27)

Name: Anti-Homer1L Antibody
Brand: NeuroMab
SKU: 75-453
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

L113/27

Applications

ICC, IHC

Host Species

Mouse

Format

Purified

Gene Name

Homer1 Vesl1

Molecular Weight

45-55 kDa

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Adult rat hippocampus immunohistochemistry.

Volume: 100 µL

Variant

Price:

$308

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Product Details

Target

Homer protein homolog 1 (Homer-1) (VASP/Ena-related gene up-regulated during seizure and LTP 1) (Vesl-1)

Target Description

Homer Scaffold Protein 1 is encoded by the gene HOMER1. Homer1 is a member of the Homer family of dendritic proteins. Homer1 is a postsynaptic density scaffolding protein which binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1, and SHANK3. HOMER1 is expressed in the skeletal muscle, heart, and brain. Diseases associated with HOMER1 include Phelan-Mcdermid Syndrome, bipolar disorder, autism, fragile x syndrome, and pervasive developmental disorder.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

L113/27

Isotype

IgG2b

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Homer1 Vesl1

Molecular Weight

45-55 kDa

Antigen

Fusion protein amino acids 121-363 (C-terminus) of mouse Homer1L (also known as Homer protein homolog 1, VASP/Ena-related gene up-regulated during seizure and LTP 1, Vesl-1, Vesl, SYN47 and PSD-Zip45, accession number Q9Z2Y3); Rat: 97% identity (236/243 amino acids identical); Human: 93% identity (226/243 amino acids identical); 30% identity with Homer1S (100% identity between amino acids 121-175, shared sequence of MELTSTPSQESAGGDLQSPLTPESINGTDDERTPDVTQNSEPRAEPTQNALPFPH); 40% identity with Homer2

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2651166

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

Does not cross-react with Homer1S

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Homer protein homolog 1 (Homer-1) (VASP/Ena-related gene up-regulated during seizure and LTP 1) (Vesl-1)

UniProt Details

UniProt (Human): Q86YM7
UniProt (Immunogen Species): Q9Z2Y3

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Anti-Homer1L Antibody (L113/27)

Anti-Homer1L Antibody
SKU: 75-453

Bulk Order Anti-Homer1L Antibody

Product Details

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Anti-Homer1L Antibody (L113/27)

Anti-Homer1L Antibody SKU: 75-453

Bulk Order Anti-Homer1L Antibody

Product Details

Anti-Homer1L Antibody
SKU: 75-453