Anti-GluR1 Antibody (RH95)

Name: Anti-GluR1 Antibody
Brand: PhosphoSolutions
SKU: 895-GluR1
Price: 430.0 USD
Availability: InStock

4 Citations

Our Anti-GluR1 primary antibody from PhosphoSolutions is mouse monoclonal. It detects mouse and rat GluR1 and is Protein G purified. It is great for use in WB.

Western blot of rat hippocampal lysate showing specific immunolabeling of the ~105 kDa GluR1 protein.

Species Reactivity

Mouse, Rat

Applications

Host Species

Mouse

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Data Sheet

Trial Size

SKU: 895-GluR1

Volume: 100 µL

Variant

Price:

$430.00

Quantity:

Product Details

Target

GluR1

Target Description

The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by α-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990;Hollmann and Heinemann, 1994).

Format

Protein G Purified

Clonality

Monoclonal

Clone

RH95

Isotype

IgG2a

Applications

Host Species

Mouse

Gene Name

GRIA1

Molecular Weight

100 kDa

Antigen

Synthetic peptide corresponding to amino acid residues from the N-terminal region of rat GluR1, conjugated to keyhole limpet hemocyanin (KLH).

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2492126

Storage

Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Physical State

Liquid

Production Notes

Protein G purified culture supernatant.

Buffer

10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.

Dilution Ranges

WB: 1:1000
WB Brain: 1:1000

Conjugate

Unconjugated

Specificity

Specific for endogenous levels of the ~105 kDa GluR1 protein.

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Shipping

Blue Ice

Synonyms

GLUR 1 antibody, GLUR A antibody, AMPA 1 antibody, AMPA selective glutamate receptor 1 antibody, AMPA-selective glutamate receptor 1 antibody, GluA1 antibody, GLUH1 antibody, GluR K1 antibody, GluR-1 antibody, GluR-A antibody, GluR-K1 antibody, GLUR1 antibody, GLURA antibody, GluRK1 antibody, Glutamate receptor 1 antibody, Glutamate receptor ionotropic AMPA 1 antibody, Glutamate receptor ionotropic antibody, Glutamate receptor, ionotropic, AMPA 1 antibody, Gria1 antibody, GRIA1_HUMAN antibody, HBGR1 antibody, MGC133252 antibody, OTTHUMP00000160643 antibody, OTTHUMP00000165781 antibody, THUMP00000224241 antibody, OTTHUMP00000224242 antibody, OTTHUMP00000224243 antibody

UniProt Details

UniProt (Immunogen Species): P19490

NCBI Gene ID

50592

Product Specific References for Applications and Species

Western Blot: Mouse| Rat

Western Blot: Mouse
PMID	Dilution	Publication
25173217	1:10,000	Mango, D., et al. 2014. Adenosine A1 receptor stimulation reduces D1 receptor-mediated GABAergic transmission from striato-nigral terminals and attenuates l-DOPA-induced dyskinesia in dopamine-denervated mice. Experimental Neurology, 261, pp.733-743.
23303927	not listed	Shen, Y., et al. 2013. Melanocortin-4 receptor regulates hippocampal synaptic plasticity through a protein kinase A-dependent mechanism. Journal of Neuroscience. 33(2):464-72.

Western Blot: Rat
PMID	Dilution	Publication
28578480	not listed	Lameth, J., et al. 2017. Acute Neuroinflammation Promotes Cell Responses to 1800 MHz GSM Electromagnetic Fields in the Rat Cerebral Cortex. Neurotoxicity Research, pp.1-16.
23303927	not listed	Shen, Y., et al. 2013. Melanocortin-4 receptor regulates hippocampal synaptic plasticity through a protein kinase A-dependent mechanism. Journal of Neuroscience 33(2):464-72.

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Product Specific Protocols

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Anti-GluR1 Antibody (RH95)

SKU: 895-GluR1

Product Details

Product Specific References for Applications and Species

Bulk Order Anti-GluR1 Antibody

Product Specific Protocols

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