Anti-Frataxin Antibody (N191/7)

Name: Anti-Frataxin Antibody
Brand: NeuroMab
SKU: 75-207
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

Available Conjugates

490

550

594

650

Product Type

Primary Antibody

Species Reactivity

Human

Clone

N191/7

Applications

ICC, WB

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

FXN FRDA X25

Molecular Weight

25 kDa

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Transfected cell immunoblot: extracts of COS cells transiently transfected with Myc-tagged Frataxin and untagged Kv2.1 plasmids and probed with N191/7 (left), 19E10 (middle) and N52A/42 (right) TC supe.

Volume: 100 µL

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Price:

$308

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Product Details

Target

Frataxin

Target Description

Frataxin is a highly conserved protein found in mitochondria. Frataxin is found many tissues including heart, spinal cord, liver, pancreas, dermal fibroblasts, peripheral blood lymphocytes and skeletal muscles. Frataxin functions as an iron chaperone involved in iron-sulfur biogenesis and heme biosynthesis and plays a role in iron homeostasis. Mutations in the Frataxin gene can result in Friederich ataxia.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N191/7

Isotype

IgG2b

Applications

ICC, WB

Host Species

Mouse

Gene Name

FXN FRDA X25

Molecular Weight

25 kDa

Antigen

Fusion protein amino acids 81-210 (C-terminus) of human Frataxin (accession number Q16595) produced recombinantly in E. Coli

Species Reactivity

Human

Antibody Registry ID

AB_11001258

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Frataxin, mitochondrial (EC 1.16.3.1) (Friedreich ataxia protein) (Fxn) [Cleaved into: Frataxin intermediate form (i-FXN); Frataxin(56-210) (m56-FXN); Frataxin(78-210) (d-FXN) (m78-FXN); Frataxin mature form (Frataxin(81-210)) (m81-FXN)]

UniProt Details

UniProt (Human): Q16595
UniProt (Immunogen Species): Q16595

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Anti-Frataxin Antibody (N191/7)

Available Conjugates

Anti-Frataxin Antibody
SKU: 75-207

Bulk Order Anti-Frataxin Antibody

Product Details

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Anti-Frataxin Antibody (N191/7)

Available Conjugates

Anti-Frataxin Antibody SKU: 75-207

Bulk Order Anti-Frataxin Antibody

Product Details

Anti-Frataxin Antibody
SKU: 75-207