Transfected cell immunoblot: extracts of COS cells transiently transfected with Myc-tagged Frataxin and untagged Kv2.1 plasmids and probed with N191/7 (left), 19E10 (middle) and N52A/42 (right) TC supe.
Frataxin is a highly conserved protein found in mitochondria. Frataxin is found many tissues including heart, spinal cord, liver, pancreas, dermal fibroblasts, peripheral blood lymphocytes and skeletal muscles. Frataxin functions as an iron chaperone involved in iron-sulfur biogenesis and heme biosynthesis and plays a role in iron homeostasis. Mutations in the Frataxin gene can result in Friederich ataxia.
FXN FRDA X25
Fusion protein amino acids 81-210 (C-terminus) of human Frataxin (also known as Fxn, Friedreich ataxia protein, FRDA and X25, accession number Q16595); Mouse: 92% identity (118/127 amino acids identical)
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
No cross-reactivity reported
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.