Anti-Cav1.3 Ca2+ Channel Antibody (L48A/9)

Name: Anti-Cav1.3 Ca2+ Channel Antibody
Brand: NeuroMab
SKU: 75-113
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

Available Conjugates

490

550

594

650

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

L48A/9

Applications

ICC, IHC, IP, WB

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

Cacna1d Cach3 Cacn4 Cacnl1a2 Cchl1a2

Molecular Weight

250 kDa

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Adult rat hippocampus immunohistochemistry.

Adult rat brain membrane immunoblot.

Volume: 100 µL

Variant

Price:

$308

Quantity:

Bulk Order Anti-Cav1.3 Ca2+ Channel Antibody

Product Details

Target

Cav1.3 Ca2+ channel

Target Description

Voltage-dependent L-type calcium channel subunit alpha-1D, or Cav1.3 calcium channel is a calcium channel encoded by the gene CACNA1D. It is a member of the L type voltage dependent calcium channel family. These calcium channels mediate the influx of calcium ions into a cell upon membrane polarization. Cav1.3 is expressed primarily in the membrane of the heart, brain (cerebral cortex, hippocampus, basal ganglia and thalamus). and pancreatic islets. Calcium channels are involved in many cell processes including muscle contraction, neurotransmitter release, gene expression, cell division and cell death. Diseases associated with Cav1.3 include Primary Aldosteronism, Seizures, Sinoatrial Node Dysfunction and Deafness.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

L48A/9

Isotype

IgG2a

Applications

ICC, IHC, IP, WB

Host Species

Mouse

Gene Name

Cacna1d Cach3 Cacn4 Cacnl1a2 Cchl1a2

Molecular Weight

250 kDa

Antigen

Synthetic peptide amino acids 859-875 (N-terminus) of rat Cav1.3 (accession number P27732)

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2069388

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.41

Conjugate

Unconjugated

Specificity

No cross-reactivity against Cav1.2

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Voltage-dependent L-type calcium channel subunit alpha-1D (Calcium channel, L type, alpha-1 polypeptide, isoform 2) (Rat brain class D) (RBD) (Voltage-gated calcium channel subunit alpha Cav1.3)

UniProt Details

UniProt (Human): Q01668
UniProt (Immunogen Species): P27732

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Anti-Cav1.3 Ca2+ Channel Antibody (L48A/9)

Available Conjugates

Anti-Cav1.3 Ca2+ Channel Antibody
SKU: 75-113

Bulk Order Anti-Cav1.3 Ca2+ Channel Antibody

Product Details

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Anti-Cav1.3 Ca2+ Channel Antibody (L48A/9)

Available Conjugates

Anti-Cav1.3 Ca2+ Channel Antibody SKU: 75-113

Bulk Order Anti-Cav1.3 Ca2+ Channel Antibody

Product Details

Anti-Cav1.3 Ca2+ Channel Antibody
SKU: 75-113