Anti-Calretinin Antibody (L122/6)

Name: Anti-Calretinin Antibody
Brand: NeuroMab
SKU: 75-488
Price: 319.0 USD
Availability: InStock

Our Anti-Calretinin mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L122/6. It detects human, mouse, and rat Calretinin, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Array tomography immunofluorescence of a single 70 nm LRWhite-embedded section from adult mouse cortex with L122/6 (green, left), rabbit Calretinin (red, right) and DAPI (blue). Images courtesy of Kristina Micheva (Stanford)..

Array tomography immunofluorescence of a single 70 nm LRWhite-embedded section from adult mouse cortex with L122/6 (green, left), rabbit Calretinin (red, right) and DAPI (blue). Images courtesy of Kristina Micheva (Stanford)..

Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC, WB

Host Species

Mouse

Available Conjugates

490

550

594

650

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Data Sheet

SKU: 75-488

Volume: 100 µL

Variant

Price:

$319.00

Quantity:

Product Details

Target

Calretinin

Target Description

Calretinin is a calcium-binding protein involved in calcium signaling. It is abundantly expressed throughout the central nervous system, retina and many other tissues. Studies have shown that calretinin may play a role in neuroprotection by buffering intracellular calcium (Lukas and Jones 1994, Weisenhorn et al., 1996). Additionally, calretinin selectively stains mesothelial cells thus making it an important marker for differentiating malignant mesothelioma from carcinomas (Attanoos et al., 2000).

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

L122/6

Isotype

IgG2b

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

CALB2 CAB29

Molecular Weight

25-35 kDa

Antigen

Fusion protein amino acids 1-178 (N-terminus) of human CALB2 (accession number) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2797368

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

CALB2 (Calretinin) (29 kDa calbindin)

UniProt Details

UniProt (Human): P22676
UniProt (Immunogen Species): P22676

Product Specific References for Applications and Species

Immunohistochemistry: Mouse

Immunohistochemistry: Mouse
PMID	Dilution	Publication
33132203	1:5 (supe)	Hawkins, N.A., et al. 2021. Epilepsy and neurobehavioral abnormalities in mice with a dominant-negative KCNB1 pathogenic variant. Neurobiological Behaviors, 105141.

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Anti-Calretinin Antibody (L122/6)

SKU: 75-488

Product Details

Product Specific References for Applications and Species

Bulk Order Anti-Calretinin Antibody

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