Array tomography immunofluorescence of a single 70 nm LRWhite-embedded section from adult mouse cortex with L122/6 (green, left), rabbit Calretinin (red, right) and DAPI (blue). Images courtesy of Kristina Micheva (Stanford)..
CALB2 (Calretinin) (29 kDa
Calretinin is a calcium-binding protein involved in calcium signaling. It is abundantly expressed throughout the central nervous system, retina and many other tissues. Studies have shown that calretinin may play a role in neuroprotection by buffering intracellular calcium (Lukas and Jones 1994, Weisenhorn et al., 1996). Additionally, calretinin selectively stains mesothelial cells thus making it an important marker for differentiating malignant mesothelioma from carcinomas (Attanoos et al., 2000).
AT, IHC, WB
Fusion protein amino acids 1-178 (N-terminus) of human CALB2
Human, Mouse, Rat
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.