Immunoblot versus crude membrane preparations from adult rat brain (RBM) and Brevican wild-type (WT) and knockout (KO) mice and probed with N294A/6 (left) and N52A/42 (right) TC supe. Mouse brain samples courtesy of Matthew Rasband, Baylor College of Medicine.
Bulk Order Anti-Brevican Antibody
Brevican core protein, Chondroitin sulfate proteoglycan 7 or Brain-enriched hyaluronan-binding protein is encoded by the gene BCAN and is a member of the lectican family of chondroitin sulfate proteoglycans. Brevican is involved in the development and formation of the brain extracellular matrix and may be involved in malignancy of brain tumor cells. Brevican is developmentally regulated and specifically expressed in the central nervous system. Diseases associated with this gene include Low-Grade Astrocytoma.
Purified by Protein A chromatography
ICC, IHC, WB
140 kDa (and smaller due to proteolytic cleavage)
Fusion protein amino acids 219-655 of rat Brevican (accession number P55068) produced recombinantly in E. Coli
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
No cross-reactivity reported
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from date of receipt
Shipped on ice packs
Brevican core protein (Brain-enriched hyaluronan-binding protein) (BEHAB)