Rho GTPase-activating protein p115 or ARHGAP4 is encoded by the gene ARHGAP4 and is a member of the RHO GTPase-activating proteins (rhoGAP) family of proteins. These proteins play a role in the regulation of small GTP-binding proteins belonging to the RAS superfamily. ARHGAP4 is thought to be involved in axonal outgrowth and the regulation of cell motility. Diseases associated with this gene include types of Diabetes.
Synthetic peptide amino acids 19-34 (AQVKEMRWQLSEQLHC, FCH domain) of mouse ARHGAP4 (also known as Rho GTPase-activating protein 4, Rho-GAP hematopoietic protein C1, p115, KIAA0131, RGC1 and RHOGAP4, accession number Q8VHL8); Rat: 87% identity (14/16 amino acids identical); Human: 87% identity (14/16 amino acids identical)
Greater than 60% identity with FNBP2
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