Anti-Ankyrin-G (Staining) Antibody FL650 Conjugate (N106/65)

Name: Anti-Ankyrin-G (Staining) Antibody FL650 Conjugate
Brand: NeuroMab
SKU: 75-147-FL650
Price: 499.0 USD
Availability: InStock

from NeuroMab Datasheet

Available Conjugates

Unconjugated

490

550

594

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

N106/65

Applications

ICC, IHC

Host Species

Mouse

Format

Purified by Protein A chromatography

Gene Name

ANK3

Molecular Weight

<200 kDa

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Volume: 200 µL

Variant

Price:

$499

Quantity:

Bulk Order Anti-Ankyrin-G (Staining) Antibody FL650 Conjugate

Product Details

Target

Ankyrin-G (Staining)

Target Description

Ankyrin-G (ankyrin 3) is a member of the Ankyrin family which consists of Ankyrin R (1), Ankyrin B (2) and Ankyrin G (3) all of which are expressed in the nervous system. Ankyrins are structural proteins that aid in the attachment of integral membrane proteins with the spectrin-actin cytoskeleton, and thus targets voltage-gated sodium channels, potassium channels, cell adhesion molecules and others at the nodes of Ranvier and axonal initial segments (AIS). Variants in Ankyrin G have been linked to bipolar disorder.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N106/65

Isotype

IgG2b

Applications

ICC, IHC

Host Species

Mouse

Gene Name

ANK3

Molecular Weight

<200 kDa

Antigen

Fusion protein ~1000 amino acids of Ankyrin-G (accession number E9PE32) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939547

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

Specificity

Does not cross-react with Ankyrin-B

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Ankyrin-3 (ANK-3) (Ankyrin-G)

UniProt Details

UniProt (Human): Q12955
UniProt (Immunogen Species): E9PE32

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Anti-Ankyrin-G (Staining) Antibody FL650 Conjugate (N106/65)

Available Conjugates

Anti-Ankyrin-G (Staining) Antibody FL650 Conjugate
SKU: 75-147-FL650

Bulk Order Anti-Ankyrin-G (Staining) Antibody FL650 Conjugate

Product Details

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Anti-Ankyrin-G (Staining) Antibody FL650 Conjugate (N106/65)

Available Conjugates

Anti-Ankyrin-G (Staining) Antibody FL650 Conjugate SKU: 75-147-FL650

Bulk Order Anti-Ankyrin-G (Staining) Antibody FL650 Conjugate

Product Details

Anti-Ankyrin-G (Staining) Antibody FL650 Conjugate
SKU: 75-147-FL650