Anti-Ankyrin-G (Blotting) Antibody FL490 Conjugate (N106/20)

Name: Anti-Ankyrin-G (Blotting) Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-187-FL490
Price: 460.0 USD
Availability: InStock

Our Anti-Ankyrin-G (Blotting) mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N106/20. It detects human, mouse, and rat Ankyrin-G (Blotting), and is purified by Protein A chromatography. It is great for use in ICC.

Species Reactivity

Human, Mouse, Non-Human Primate, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

Unconjugated

550

594

650

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Data Sheet

SKU: 75-187-FL490

Volume: 200 µL

Variant

Price:

$460.00

Quantity:

Product Details

Target

Ankyrin-G (Blotting)

Target Description

Ankyrin-G (ankyrin 3) is a member of the Ankyrin family which consists of Ankyrin R (1), Ankyrin B (2) and Ankyrin G (3) all of which are expressed in the nervous system. Ankyrins are structural proteins that aid in the attachment of integral membrane proteins with the spectrin-actin cytoskeleton, and thus targets voltage-gated sodium channels, potassium channels, cell adhesion molecules and others at the nodes of Ranvier and axonal initial segments (AIS). Variants in Ankyrin G have been linked to bipolar disorder.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N106/20

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

ANK3

Molecular Weight

>200 kDa

Antigen

Fusion protein ~1000 amino acids of Ankyrin-G (accession number E9PE32) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Non-Human Primate, Rat

Antibody Registry ID

AB_2939692

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Ankyrin-3 (ANK-3) (Ankyrin-G)

UniProt Details

UniProt (Human): Q12955
UniProt (Immunogen Species): E9PE32

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Anti-Ankyrin-G (Blotting) Antibody FL490 Conjugate (N106/20)

SKU: 75-187-FL490

Product Details

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