Anti-AGPS Neo-Epitope Antibody (N444/63)

Name: Anti-AGPS Neo-Epitope Antibody
Brand: NeuroMab
SKU: 75-434
Price: 337.0 USD
Availability: InStock

Our mouse AGPS neo-epitope monoclonal antibody from NeuroMab is produced in-house from clone N444/63. It detects human, mouse, and rat AGPS neo-epitope and is purified by Protein A chromatography. Works in WB, IHC, ICC, ELISA.

Adult rat hippocampus immunohistochemistry.

Adult rat brain membrane (RBM) and human cell immunoblot: lysates of RBM and fibroblasts from unaffected (control/normal) and disease-affected (patient/Pex5-mutant) humans probed with N444/63 TC supe (left) and rabbit polyclonal (right). Human fibroblast samples courtesy of Ning Huang and Joseph Hacia (USC) and rabbit polyclonal courtesy of Nancy Braverman (McGill).

Adult rat hippocampus immunohistochemistry.

Click on image to zoom

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

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Data Sheet

SKU: 75-434

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

AGPS neo-epitope

Scientific Background

Alkyldihydroxyacetonephosphate synthase, peroxisomal or AGPS neo-epitope is encoded by the gene AGPS. AGPS is a member of the FAD-binding oxidoreductase/transferase type 4 family and is an enzyme involved in ether lipid biosynthesis. Diseases associated with this gene include forms of Rhizomelic Chondrodysplasia Punctata.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N444/63

Isotype

IgG1

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

AGPS AAG5

Molecular Weight

66 kDa processed (vs. 72 kDa unprocessed)

Immunogen

Synthetic peptide amino acids 59-67 (KARRAASAA, site of proteolytic processing for peroxisome import) of human AGPS (accession number O00116)

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2629423

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Does not cross-react with unprocessed AGPS

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Alkyldihydroxyacetonephosphate synthase, peroxisomal (Alkyl-DHAP synthase) (EC 2.5.1.26) (Aging-associated gene 5 protein) (Alkylglycerone-phosphate synthase)

UniProt ID

O00116

Shipping

Shipped on ice packs

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Anti-AGPS Neo-Epitope Antibody (N444/63)

SKU: 75-434

Product Details

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