Alkyldihydroxyacetonephosphate synthase, peroxisomal or AGPS neo-epitope is encoded by the gene AGPS. AGPS is a member of the FAD-binding oxidoreductase/transferase type 4 family and is an enzyme involved in ether lipid biosynthesis. Diseases associated with this gene include forms of Rhizomelic Chondrodysplasia Punctata.
Purified by Protein A chromatography
ICC, IHC, WB
66 kDa processed (vs. 72 kDa unprocessed)
Synthetic peptide amino acids 59-67 (KARRAASAA, site of proteolytic processing for peroxisome import) of human AGPS (accession number O00116)
Human, Mouse, Rat
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Does not cross-react with unprocessed AGPS
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.