Anti-AGPS Neo-Epitope Antibody (N444/63)

Name: Anti-AGPS Neo-Epitope Antibody
Brand: NeuroMab
SKU: 75-434
Price: 308.0 USD
Availability: InStock

from NeuroMab Datasheet

Product Type

Primary Antibody

Species Reactivity

Human, Mouse, Rat

Clone

N444/63

Applications

ICC, IHC, WB

Host Species

Mouse

Format

Purified

Gene Name

AGPS AAG5

Molecular Weight

66 kDa processed (vs. 72 kDa unprocessed)

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Adult rat brain membrane (RBM) and human cell immunoblot: lysates of RBM and fibroblasts from unaffected (control/normal) and disease-affected (patient/Pex5-mutant) humans probed with N444/63 TC supe (left) and rabbit polyclonal (right). Human fibroblast samples courtesy of Ning Huang and Joseph Hacia (USC) and rabbit polyclonal courtesy of Nancy Braverman (McGill).

Adult rat hippocampus immunohistochemistry.

Volume: 100 µL

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Product Details

Target

Alkyldihydroxyacetonephosphate synthase, peroxisomal (Alkyl-DHAP synthase) (EC 2.5.1.26) (Aging-associated gene 5 protein) (Alkylglycerone-phosphate synthase)

Target Description

Alkyldihydroxyacetonephosphate synthase, peroxisomal or AGPS neo-epitope is encoded by the gene AGPS. AGPS is a member of the FAD-binding oxidoreductase/transferase type 4 family and is an enzyme involved in ether lipid biosynthesis. Diseases associated with this gene include forms of Rhizomelic Chondrodysplasia Punctata.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N444/63

Isotype

IgG1

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

AGPS AAG5

Molecular Weight

66 kDa processed (vs. 72 kDa unprocessed)

Antigen

Synthetic peptide amino acids 59-67 (KARRAASAA, site of proteolytic processing for peroxisome import) of human AGPS (also known as Alkylglycerone-phosphate synthase, Peroxisomal alkyldihydroxyacetonephosphate synthase, Alkyl-DHAP synthase, Aging-associated gene 5 protein, Ads and AAG5, accession number O00116); Mouse: 100% identity (9/9 amino acids identical); Rat: 100% identity (9/9 amino acids identical)

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2629423

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

Does not cross-react with unprocessed AGPS

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Alkyldihydroxyacetonephosphate synthase, peroxisomal (Alkyl-DHAP synthase) (EC 2.5.1.26) (Aging-associated gene 5 protein) (Alkylglycerone-phosphate synthase)

UniProt Details

UniProt (Human): O00116
UniProt (Immunogen Species): O00116

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Anti-AGPS Neo-Epitope Antibody (N444/63)

Anti-AGPS Neo-Epitope Antibody
SKU: 75-434

Bulk Order Anti-AGPS Neo-Epitope Antibody

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Anti-AGPS Neo-Epitope Antibody (N444/63)

Anti-AGPS Neo-Epitope Antibody SKU: 75-434

Bulk Order Anti-AGPS Neo-Epitope Antibody

Product Details

Anti-AGPS Neo-Epitope Antibody
SKU: 75-434