AM3-25 Nerve Terminal Dye
Our AM3-25 Nerve Terminal Dye is a fixable far-red nerve terminal probe.
SKU: 81-8021
Ships: 1-5 business days
Product Details
Nerve terminal dyes have highly hydrophilic, cationically charged head groups at one end with lipophilic tails at the other end. They are virtually non-fluorescent in aqueous solution, but become intensely fluorescent in membranes. Following nerve stimulation, the dye molecules are internalized in newly formed endocytic vesicles. During exocytosis, the dyes are released from the vesicles along with neurotransmitters, causing a decrease in fluorescence signal. As a result, the change in fluorescent intensity reflects the amount of endocytosis/exocytosis or synaptic activity. AM3-25 is a lipophilic styryl dye that has an amine group at the hydrophilic head. The amine group reacts with formaldehyde or glutaldehyde to make the dye fixable.
EM, ICC, IHC
952.83 Da
Ex: 480 nm, Em: 600 nm (in membranes)
Store at 2°C to 8°C, with desiccant; protect from light.
Solid
For use in real-time imaging of live/intact cells and cells fixed after staining in formaldehyde.
For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
United States
Stable for 12 months after date of receipt.
Shipped at ambient temperature with desiccant; protected from light

