SynaptoGreenTM C18 (equivalent to FM®3-25) Nerve Terminal Dye
Our SynaptoGreenTM C18 Nerve Terminal Dye is a widely used green fluorescent dye for following synaptic activity by staining synaptic vesicles at the synapse or neuromuscular junctions.
SKU: 81-8017
Ships: 1-5 business days
Product Details
Nerve terminal dyes have highly hydrophilic, cationically charged head groups at one end with lipophilic tails at the other end. They are virtually non-fluorescent in aqueous solution, but become intensely fluorescent in membranes. Following nerve stimulation, the dye molecules are internalized in newly formed endocytic vesicles. During exocytosis, the dyes are released from the vesicles along with neurotransmitters, causing a decrease in fluorescence signal. As a result, the change in fluorescent intensity reflects the amount of endocytosis/exocytosis or synaptic activity. SynaptoGreenTM C18 is a widely used green fluorescent dye for following synaptic activity by staining synaptic vesicles at the synapse or neuromuscular junctions. SynaptoGreen™ C18 (equivalent to FM®3-25) is a membrane stain with a chemical structure similar to other nerve terminal dyes, except that it has the longest lipophilic tail (C18). Because of its large size, it is used as a control for ion channel permeability of nerve terminal dyes.
EM, ICC, IHC
1004 Da
Ex: 480 nm, Em: 598 nm (in membranes)
Store at 2°C to 8°C, with desiccant; protect from light.
Solid
For use in real-time imaging of live/intact cells.
For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
United States
Stable for 12 months after date of receipt.
FM3-25
Shipped at ambient temperature with desiccant; protected from light