SGC5 Nerve Terminal Dye

Name: SGC5 Nerve Terminal Dye
Brand: Antibodies Incorporated
SKU: 81-8027
Price: 279.0 USD
Availability: InStock

Our SGC5 Nerve Terminal Dye is similar to the FM® dyes and can be used on live/intact cells where it becomes highly fluorescent upon insertion into lipid bilayers.

Applications

EM, ICC, IHC

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Data Sheet

SKU: 81-8027

Size: 1 mg

Variant

Price:

$279.00

Quantity:

Ships: 1-5 business days

Product Details

Scientific Background

Nerve terminal dyes have highly hydrophilic, cationically charged head groups at one end with lipophilic tails at the other end. They are virtually non-fluorescent in aqueous solution, but become intensely fluorescent in membranes. Following nerve stimulation, the dye molecules are internalized in newly formed endocytic vesicles. During exocytosis, the dyes are released from the vesicles along with neurotransmitters, causing a decrease in fluorescence signal. As a result, the change in fluorescent intensity reflects the amount of endocytosis/exocytosis or synaptic activity. SGC5 is a coumarin styryl dye that binds to membranes in a manner similar to the FM® dyes. It becomes highly fluorescent upon insertion into lipid bilayers.

Applications

EM, ICC, IHC

Molecular Weight

682 Da

Excitation / Emission

Ex: 484 nm, Em: 563 nm

Storage

Store at 2°C to 8°C, with desiccant; protect from light.

Physical State

Solid

Specificity

For use in real-time imaging of live/intact cells.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Country of Origin

United States

Expiration

Stable for 12 months after date of receipt.

Shipping

Shipped at ambient temperature with desiccant; protected from light

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SGC5 Nerve Terminal Dye

SKU: 81-8027

Product Details

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