SCFR-Fc Chimera, Human, Purified Recombinant Protein

Name: SCFR-Fc Chimera, Human, Purified Recombinant Protein
Brand: Biosensis
SKU: PE-1244-50
Price: 527.0 USD
Availability: InStock

Stem cell factor receptor (SCFR)-Fc Chimera, purified human recombinant protein, suitable to block.

Applications

Block

Host Species

HEK293

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Data Sheet

SKU: PE-1244-50

Volume/Size: 50 µg

Variant

Price:

$527.00

Quantity:

Product Details

Target

Stem cell factor receptor (SCFR)

Scientific Background

Stem Cell Factor Receptor (SCFR) is a member of the receptor tyrosine kinase family. Binding of SCFR to its ligand Stem Cell Factor (PE-2008-5) induces receptor dimerization, autophosphorylation and signal transduction. SCFR is essential for the development of normal hematopoietic cells and plays an important role in the survival, proliferation and differentiation of mast cells, melanocytes and germ cells.

Format

Purified. The SCFR-Fc Chimera consists of 5-45% carbohydrate by weight.

Applications

Block

Host Species

HEK293

Protein Sequence

A DNA sequence encoding the signal peptide and extracellular domain of human Stem Cell Factor Receptor (amino acids 1-520) was fused to the Fc region of human IgG1 (amino acids 93-330). The chimeric protein was expressed in modified human 293 cells.

Storage

It is recommended that 0.5 mL of sterile phosphate-buffered saline be added to the vial. Lyophilized products should be stored at 2 to 8°C. Following reconstitution short-term storage at 2-8°C is recommended, and longer-term storage of aliquots at -18 to -20°C. Repeated freeze thawing is not recommended.

Physical State

Lyophilized

Production Notes

>95% purity, as determined by SDS-PAGE and visualized by silver stain

Buffer

When reconstituted in 0.5 mL sterile phosphate-buffered saline, the solution will contain 1% human serum albumin (HSA) and 10% trehalose.

Usage Statement

For research use only.

Country of Origin

United States

Expiration

12 months after date of receipt (unopened vial).

Synonyms

Mast/stem cell growth factor receptor; SCFR; Proto-oncogene tyrosine-protein kinase Kit; c-kit; CD117

UniProt ID

P10721

Shipping

25°C (ambient)

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SCFR-Fc Chimera, Human, Purified Recombinant Protein

SKU: PE-1244-50

Product Details

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