Anti-ADAM22 (Cytoplasmic) Antibody (N46/30)

Our Anti-ADAM22 (cytoplasmic) mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N46/30. It is KO validated, detects human, mouse, and rat ADAM22 (cytoplasmic), and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.



SKU: 75-083

Volume: 100 µL
1-2 business days
Price:
Sale price$319

Product Specific References for Applications and Species

Immunocytochemistry: Human
PMID Dilution Publication
37953841not listedNosková, L, et al. 2023. ADAM22 ethnic-specific variant reducing binding of membrane-associated guanylate kinases causes focal epilepsy and behavioural disorder. Brain Communications, .
Immunocytochemistry: Rat
PMID Dilution Publication
311648061:100Bonetto, G., et al. 2019. Selective Axonal Expression of the Kv1 Channel Complex in Pre-myelinated GABAergic Hippocampal Neurons. Frontiers in cellular neuroscience, 222.
305985021:100Hivert, B., et al. 2019. ADAM22 and ADAM23 modulate the targeting of the Kv1 channel-associated protein LGI1 to the axon initial segment. Journal of cell science, jcs219774.
Immunohistochemistry: Mouse
PMID Dilution Publication
26269648not listedKole, M., et al. 2015. Selective Loss of Presynaptic Potassium Channel Clusters at the Cerebellar Basket Cell Terminal Pinceau in Adam11 Mutants Reveals Their Role in Ephaptic Control of Purkinje Cell Firing. The Journal of neuroscience : the official journal of the Society for Neuroscience, 11433-11444.
Immunohistochemistry: Rat
PMID Dilution Publication
20089912not listedOgawa, Y., et al. 2010. ADAM22, a Kv1 channel-interacting protein, recruits membrane-associated guanylate kinases to juxtaparanodes of myelinated axons. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1038-1048.
Immunoprecipitation: Mouse
PMID Dilution Publication
296701001:250Yamagata, A., et al. 2018. Structural basis of epilepsy-related ligand-receptor complex LGI1-ADAM22. Nature communications, 1546.
Western Blot: Human
PMID Dilution Publication
22473675not listedDhanchak, A., et al. 2012. Implication of perturbed axoglial apparatus in early pediatric multiple sclerosis. Annals of neurology, 601-613.
20463223not listedThomas, R., et al. 2010. LGI1 is a Nogo receptor 1 ligand that antagonizes myelin-based growth inhibition. The Journal of neuroscience : the official journal of the Society for Neuroscience, 6607-6612.
Western Blot: Mouse
PMID Dilution Publication
34910912not listedYokoi, N., et al. 2021. 14-3-3 proteins stabilize LGI1-ADAM22 levels to regulate seizure thresholds in mice. Cell reports, 110107.
308463101:200Tai, Y., et al. 2019. Axo-axonic Innervation of Neocortical Pyramidal Neurons by GABAergic Chandelier Cells Requires AnkyrinG-Associated L1CAM. Neuron, 358-372.
28452394not listedFrank, R., et al. 2017. Hierarchical organization and genetically separable subfamilies of PSD95 postsynaptic supercomplexes. Journal of neurochemistry, 504-511.
262696481:200Kole, M., et al. 2015. Selective Loss of Presynaptic Potassium Channel Clusters at the Cerebellar Basket Cell Terminal Pinceau in Adam11 Mutants Reveals Their Role in Ephaptic Control of Purkinje Cell Firing. The Journal of neuroscience : the official journal of the Society for Neuroscience, 11433-11444.
25707359not listedChen, N., et al. 2015. Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes. Biochimica et biophysica acta, 827-833.
197012041:1000Zhou, Y., et al. 2009. Arrested maturation of excitatory synapses in autosomal dominant lateral temporal lobe epilepsy. Nature medicine, 1208-1214.

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