Anti-LAR/PTPRF (Receptor-Type Tyrosine-Protein Phosphatase) Antibody (N165/38)

Name: Anti-LAR/PTPRF (Receptor-Type Tyrosine-Protein Phosphatase) Antibody
Brand: NeuroMab
SKU: 75-193
Price: 337.0 USD
Availability: InStock

Our mouse LAR/PTPRF (Receptor-type tyrosine-protein phosphatase) monoclonal antibody from NeuroMab is produced in-house from clone N165/38. It detects human, mouse, and rat LAR/PTPRF (Receptor-type tyrosine-protein phosphatase) and is purified by Protein A chromatography. Works in WB, ICC, ELISA.

Adult rat brain membrane immunoblot.

Click on image to zoom

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, WB

Host Species

Mouse

Conjugates and Formulations

490

550

594

650

Biotin

Carrier-Free

Go to Full Product Details

Data Sheet

SKU: 75-193

Volume: 100 µL

Variant

Price:

$337.00

Quantity:

Ships: 1-2 business days

Product Details

Target

LAR/PTPRF (Receptor-type tyrosine-protein phosphatase)

Scientific Background

Receptor-type tyrosine-protein phosphatase F or Leukocyte Common Antigen Related protein is encoded by the gene PTPRF and is a member of the protein tyrosine phosphatase (PTP) family. PRPRF is a transmembrane protein involved in regulation of insulin signaling, cell proliferation and cell migration. PTPRF functions in the regulation of epithelial cell-cell contacts at adherens junctions, as well as in the control of beta-catenin signaling. PTPRF is ubiquitously expressed. Diseases associated with PTPRF include Aplasia or hypoplasia of the breasts and/or nipples 2

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N165/38

Isotype

IgG2a

Applications

ELISA, ICC, WB

Host Species

Mouse

Gene Name

PTPRF LAR

Molecular Weight

85 kDa (full-length is 210 kDa, smaller due to proteolysis into P-subunit containing transmembrane and intracellular domains)

Immunogen

Fusion protein amino acids 1315-1607 (cytoplasmic C-terminus) of human LAR (accession number P10586) produced recombinantly in E. Coli

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_10675291

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.121

Conjugate

Unconjugated

Specificity

Does not cross-react with PTPRD or PTPRS

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Receptor-type tyrosine-protein phosphatase F (EC 3.1.3.48) (Leukocyte common antigen related) (LAR)

UniProt ID

P10586

Shipping

Shipped on ice packs

Recover password

Create my account

Anti-LAR/PTPRF (Receptor-Type Tyrosine-Protein Phosphatase) Antibody (N165/38)

SKU: 75-193

Product Details

Bulk Order Anti-LAR/PTPRF (Receptor-Type Tyrosine-Protein Phosphatase) Antibody

Related Products

Recently Viewed