alpha-Bungarotoxin

Name: alpha-Bungarotoxin
Brand: Antibodies Incorporated
SKU: 81-1200
Price: 219.0 USD
Availability: InStock

Our alpha-Bungarotoxin is a potent neurotoxin widely used to study neuromuscular junctions by blocking cholinergic receptors. Membrane impermeant, it works well in live/intact cells and cells fixed in formaldehyde or methanol.

alpha-Bungarotoxin

Click on image to zoom

Applications

EM, ICC, IHC

Go to Full Product Details

Data Sheet

SKU: 81-1200

Size: 1 mg

Variant

Price:

$219.00

Quantity:

Ships: 1-5 business days

Product Details

Scientific Background

alpha-Bungarotoxin is a high affinity inhibitor (Kd = 1 nM to 1 pM) of the nicotinic acetylcholine receptor in the neuromuscular junction and blocks acetylcholine activity at the postsynaptic membrane. It is often used to study neuromuscular junctions by blocking cholinergic receptors. The effects of α-bungarotoxin on neuronal nAChR have been shown to be highly specific for the α7-subtype (IC50 = 1.6 nM), but not for the α3β4-subtype (IC50 >3 µM). Labeled α-bungarotoxin conjugates can be used for staining nicotinic acetylcholine receptors at neuromuscular junctions in tissue sections.

Applications

EM, ICC, IHC

Molecular Weight

7984 Da

Excitation / Emission

Unconjugated

Storage

Store at –20°C, with desiccant.

Physical State

Solid

Conjugate

Unconjugated

Specificity

Membrane impermeant; works in live/intact cells and cells fixed in formaldehyde or methanol.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Country of Origin

United States

Expiration

Stable for 12 months after date of receipt.

Synonyms

neurotoxin, nicotinic (a7) receptor antagonist

Shipping

Shipped at ambient temperature with desiccant

Recover password

Create my account

alpha-Bungarotoxin

SKU: 81-1200

Product Details

Bulk Order alpha-Bungarotoxin

Related Products

Recently Viewed