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Products: Primary Antibodies

Anti-Flrt3 Antibody (N353/13)

NeuroMab Logo from NeuroMab

 Datasheet

PRODUCT OPTIONS

Brand Catalog # Option Volume Concentration Price
Brand
NeuroMab Logo
Catalog #
75-328
Option
Purified
Volume
100 µL
Concentration
1 mg/mL
Price
$275.00
Brand
NeuroMab Logo
Catalog #
73-328
Option
TC Supernatant
Volume
5 mL
Concentration
Lot dependent
Price
$275.00

Validation Images


Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG1

Species Reactivity:

Mouse

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

ICC

Target Description:

Fibronectin Leucine Rich Transmembrane Protein 3 is encoded by the gene FLRT3. FLRT3 is a member of the fibronectin leucine rich transmembrane (FLRT) family. FLRT3 functions in cell-cell adhesion, cell migration, and axon guidance, exerting an attractive or repulsive role depending on its interaction partners. FLRT3 is expressed in adult brain, embryonic rostral thalamus neurons, and the neonate eye. Diseases associated with FLRT3 included Hypogonadotropic Hypogonadism 21 With or Without Anosmia, Kallmann Syndrome, and Hypogonadotropic Hypogonadism 7 With or Without Anosmia.

Immunogen:

Fusion protein amino acids 29-526 (extracellular domain) of mouse Flrt3 (also known as Leucinerich repeat transmembrane protein FLRT3, Fibronectin-like domain-containing leucine-rich transmembrane protein 3, KIAA1469 and UNQ856/PRO1865, accession number Q8BGT1)
Rat: 99% identity (496/498 amino acids identical)
Human: 96% identity (480/498 amino acids identical)
50% identity with Flrt1 and Flrt2

Cross Reactivity:

No cross-reactivity against Flrt1 or Flrt2

Protein Name(s):

Leucine-rich repeat transmembrane protein FLRT3 (Fibronectin leucine rich transmembrane protein 3)

Gene Name(s):

Flrt3 Kiaa1469

Antibody Registry ID:

Purified: AB_2315833
TC Supernatant: AB_2315832


Antibody Validation and Application Notes


This antibody has been validated using the following assays:
Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.


Quality Control


The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.