Anti-Centromere Protein Antibody - FITC Labeled
Our Anti-Centromere proteins human polyclonal primary antibody from Antibodies Incorporated is produced in-house. It detects Centromere proteins, and is purified by Protein A chromatography. It is great for use in ICC.
 
                 
                Representative images of heterozygous (top) and homozygous (bottom) fibroblasts stained with AURKB (C, prophase) or survivin (metaphase, D) (red; shown in grayscale) and FITC-conjugated CREST (Cat. 15-235-F, 1:100, green; shown in grayscale). Image from publication CC-BY-4.0. PMID:28272472
                           
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            SKU: 15-235-F
Product Details
                        Purified IgG derived from Human anti-Centromere positive serum (also known as CREST patient serum) conjugated to fluorescein isothiocyanate. Centromere refers to the DNA region where the kinetochore complex assembles, though these terms are often used interchangeably. Anti-Centromere Antibodies (derived from human CREST patient serum) are useful as controls in ANA diagnostics and also reacts with other species including mouse, rat, and hamster.
                      
                    
                        Adsorptive Chromatography
                      
                    
                        Lot dependent (1-2 mg/mL)
                      
                    
                        Polyclonal
                      
                    
                        ICC
                      
                    
                        Human
                      
                    
                        n/a
                      
                    
                        Hamster, Human, Mouse, Rat
                      
                    
                        AB_2797147
                      
                    
                        Liquid
                      
                    
                        FITC
                      
                    
                        Serum obtained from an autoimmune patient was purified by protein A chromatography and then tested at a series of dilutions by immunocytochemistry on ethanol-fixed Hep2 cells that were in log-phase growth. The staining pattern obtained was consistent with the pattern expected for anti-centromere staining.
                      
                    
                        These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
                      
                    
                        United States
                      
                    
                        24 months from opening
                      
                    
                        CREST, Centromere
                      
                    
 
                