Recombinant Rat TNFSF11 (RANKL)

Name: Recombinant Rat TNFSF11 (RANKL)
Brand: ImmunoChemistry Technologies
SKU: 6552
Price: 200.0 USD
Availability: InStock

Tumor necrosis factor ligand superfamily member 11 (TNFSF11), also known as Receptor Activator of Nuclear factor Kappa-B Ligand (RANKL), is a member of the tumor necrosis factor (TNF) ligand family. RANKL regulates bone remodeling and the development of the thymus, lymph nodes and mammary glands. Rat TNFSF11 (RANKL) Recombinant Protein is purified TNFSF11 (RANKL) produced in yeast.

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SKU: 6552

Volume: 5 µg

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Price:

$200.00

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Ships: 1-2 business days

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Scientific Background

Tumor necrosis factor ligand superfamily member 11 (TNFSF11), also known as Receptor Activator of Nuclear factor Kappa-B Ligand (RANKL), TNF-related activation-induced cytokine (TRANCE), osteoprotegerin ligand (OPGL), and osteoclast differentiation factor (ODF), is a member of the tumor necrosis factor (TNF) ligand family. Nineteen cytokine ligands have been identified as part of the TNF family on the basis of sequence, functional, and structural similarities. Family members include TNF beta (TNFSF1), TNF alpha (TNFSF2), Lymphotoxin beta (TNFSF3), OX40 Ligand (TNFSF4), CD40 Ligand (TNFSF5), Fas Ligand (TNFSF6), CD27 Ligand (TNFSF7), CD30 Ligand (TNFSF8), 4-1BB Ligand (TNFSF9), TRAIL (TNFSF10), TRANCE/RANKL (TNFSF11), TWEAK (TNFSF12), APRIL(TNFSF13), BAFF (TNFSF13B), LIGHT (TNFSF14), TL1A/VEGI (TNFSF15), and GITR Ligand (TNFSF18). RANKL regulates bone remodeling and the development of the thymus, lymph nodes and mammary glands. Overproduction of RANKL is implicated in a variety of degenerative bone diseases, such as rheumatoid arthritis and psoriatic arthritis.

Format

Lyophilized

Protein Sequence

FSGVPAMMEG SWLDVARRGK PEAQPFAHLT INAANIPSGS HKVSLSSWYH DRGWAKISNM TLSNGKLRVN QDGFYYLYAN ICFRHHETSG SVPADYLQLM VYVVKTSIKI PSSHNLMKGG STKNWSGNSE FHFYSINVGG FFKLRAGEEI SVQVSNPSLL DPDQDATYFG AFKVQDID (178)

Source

Yeast

Contents

Recombinant proteins produced in yeast

Usage Statement

For research use only. Not for use in diagnostic procedures.

Country of Origin

United States

Storage

-20°C

Shipping

Ships at ambient temperature, Domestic: Overnight Delivery; International: Priority Shipping

The Rat TNFSF11/RANKL protein can be used in cell culture, as an TNFSF11/RANKL ELISA Standard, and as a Western Blot Control.

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Recombinant Rat TNFSF11 (RANKL)

SKU: 6552

Product Details

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