Anti-Presenilin-1 (PS-1) Antibody

Name: Anti-Presenilin-1 (PS-1) Antibody
Brand: Biosensis
SKU: C-1534-500
Price: 337.0 USD
Availability: InStock

Our Anti-Presenilin-1 (PS-1) chicken polyclonal primary antibody detects human, mouse, and rat Presenilin-1 (PS-1), and is affinity-purified. It is validated for use in ELISA, WB.

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, WB

Host Species

Chicken

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Data Sheet

SKU: C-1534-500

Volume/Size: 500 µL

Variant

Price:

$337.00

Quantity:

Product Details

Target

Presenilin-1 (PS-1)

Scientific Background

Presenilin-1 (PSEN1) is a multi-pass membrane protein and component of the gamma-secretase complex. PSEN1 is thought to play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. It may also play a role in hematopoiesis. Defects in PSEN1 are a cause of Alzheimer disease type 3 (AD3), a familial early-onset form of Alzheimer disease (Ref:SWISS-Prot).

Format

Affinity-purified

Clonality

Polyclonal

Isotype

IgY

Applications

ELISA, WB

Host Species

Chicken

Immunogen

Mixture of two human Presenilin 1 peptides (311-322 and 341-352 aa). Both sequences are highly conserved in human, mouse and rat.

Immunogen Species

Human

Species Reactivity

Human, Mouse, Rat

Storage

Short term storage at 2-8°C for one week. At -20°C as an undiluted liquid for up to 12 months.

Physical State

Liquid

Buffer

PBS with 0.02% sodium azide.

Dilution Ranges

WB: 1:1000-1:4000
ELISA: 1:1000-1:4000

Application Details

To minimize background staining, a higher concentration of detergent (such as Tween-20) is suggested in the dilution and washing steps.

Conjugate

Unconjugated

Specificity

Human Presenilin 1.

Usage Statement

For research use only.

Country of Origin

United States

Expiration

12 months after date of receipt (unopened vial).

Synonyms

Presenilin 1; PS-1; Protein S182; PS1-CTF12; PSEN1; AD3; PS1; PSNL1;

UniProt ID

P49768

Shipping

2-8°C (on cold packs)

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Anti-Presenilin-1 (PS-1) Antibody

SKU: C-1534-500

Product Details

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