Anti-Cerebral dopamine neurotrophic factor (CDNF) Antibody

Name: Anti-Cerebral dopamine neurotrophic factor (CDNF) Antibody
Brand: Biosensis
SKU: M-1676-100
Price: 457.0 USD
Availability: InStock

Our Anti-Cerebral dopamine neurotrophic factor (CDNF) mouse monoclonal primary antibody detects human Cerebral dopamine neurotrophic factor (CDNF), and is IgG. It is validated for use in WB.

Western Blot testing of anti-CDNF antibody. Line 1. PageRuler Prestained Protein Ladder (#SM0671 Fermentas); Line 2. Recombinant CDNF expressed into the supernatant of CHO cell culture medium.

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Species Reactivity

Human

Applications

Host Species

Mouse

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Data Sheet

SKU: M-1676-100

Volume/Size: 100 µg

Variant

Price:

$457.00

Quantity:

Product Details

Target

Cerebral dopamine neurotrophic factor (CDNF)

Scientific Background

CDNF (conserved dopamine neurotrophic factor) is a trophic factor for midbrain dopamine neurons in vivo. It prevents the 6-OHDA- (Lindholm et al. 20007; Voutilainen et al., 2011) and MPTP-induced degeneration (Airavaara et al., 2012) of dopamine neurons in rodent models of Parkinson's disease. When administered after 6-OHDA or MPTP -lesioning it restores the dopaminergic function and prevents degeneration of dopamine neurons in substantia nigra pars compacta.

Format

IgG

Clonality

Monoclonal

Isotype

IgG1

Applications

Host Species

Mouse

Immunogen

Recombinant human CDNF protein produced using CHO-based cell line. Purified from cell culture supernatant.

Immunogen Species

Human

Species Reactivity

Human

Storage

Store at -20°C or -70°C upon receipt. After opening maintain undiluted in smaller aliquots at -20°C or -70°C for up to 6 months. Avoid multiple freeze-thaw cycles.

Physical State

Liquid

Production Notes

Purified by protein G affinity chromatography

Buffer

PBS pH 7.4, with 0.1% sodium azide

Dilution Ranges

WB: 1:2000-1:4000

Conjugate

Unconjugated

Specificity

CDNF (conserved dopamine neurotrophic factor).

Usage Statement

For research use only.

Country of Origin

United States

Expiration

12 months after date of receipt (unopened vial).

Synonyms

ARMETL1

UniProt ID

Q49AH0

Shipping

25°C (ambient)

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Anti-Cerebral dopamine neurotrophic factor (CDNF) Antibody

SKU: M-1676-100

Product Details

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