Anti-Homer1 Recombinant Chicken Chimeric mAb FL650 Conjugate (L113/130)

Name: Anti-Homer1 Recombinant Chicken Chimeric mAb FL650 Conjugate
Brand: Aves Labs
SKU: 78-454-FL650
Price: 549.0 USD
Availability: InStock

Our chicken Anti-Homer1 recombinant monoclonal antibody is a chimeric antibody derived from NeuroMab clone L113/130. It detects human, mouse, and rat Homer1, and is purified by affinity chromatography. It is great for use in AT, IHC, ICC.

Anti-Homer1 Recombinant Chicken Chimeric mAb FL650 Conjugate

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Applications

AT, ICC, IHC

Host Species

Chicken

Conjugates and Formulations

Unconjugated

490

550

594

Carrier-Free

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Data Sheet

SKU: 78-454-FL650

Volume: 200 µL

Variant

Price:

$549.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Homer1

Scientific Background

Homer Scaffold Protein 1 is encoded by the gene HOMER1. Homer1 is a member of the Homer family of dendritic proteins. Homer1 is a postsynaptic density scaffolding protein which binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1, and SHANK3. HOMER1 is expressed in the skeletal muscle, heart, and brain. Diseases associated with HOMER1 include Phelan-Mcdermid Syndrome, bipolar disorder, autism, fragile x syndrome, and pervasive developmental disorder.

Format

Purified by affinity chromatography

Concentration

0.5 mg/mL

Clonality

Recombinant

Clone

L113/130

Isotype

IgY

Applications

AT, ICC, IHC

Host Species

Chicken

Gene Name

Homer1 Vesl1

Molecular Weight

50 kDa

Excitation / Emission

FL650 Ex: 655 nm, Em: 676 nm

Immunogen

Fusion protein amino acids 121-363 (C-terminus) of mouse Homer1 (accession number Q9Z2Y3) produced recombinantly in E. Coli

Immunogen Species

Mouse

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

This recombinant antibody is a chimeric antibody created by replacing the mouse heavy and light constant regions of clone L113/130 with chicken IgY heavy and light constant regions. As such this antibody retains the same binding performance as the original clone L113/130 but can be detected using standard anti-chicken secondary antibodies allowing flexibility for multiplexing applications. This antibody is expressed recombinantly in mammalian cells and then affinity purified from the cell culture media and conjugated.

Buffer

1X PBS, 0.05% Sodium Azide pH 7.4

Dilution Ranges

IHC: 1:100
ICC: 1:100

Conjugate

650

Specificity

No cross-reactivity reported

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Homer protein homolog 1 (Homer-1) (VASP/Ena-related gene up-regulated during seizure and LTP 1) (Vesl-1)

UniProt ID

Q9Z2Y3

Shipping

Shipped on ice packs

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Anti-Homer1 Recombinant Chicken Chimeric mAb FL650 Conjugate (L113/130)

SKU: 78-454-FL650

Product Details

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