Anti-Apolipoprotein E (ApoE) Antibody
Our Anti-Apolipoprotein E (ApoE) goat polyclonal primary antibody detects human Apolipoprotein E (ApoE), and is affinity-purified. It is validated for use in ELISA.
SKU: G-1784-100
Product Details
Apolipoprotein E (ApoE)
Apolipoprotein E (ApoE) is a lipoprotein involved in fat metabolism and acts as cholesterol carrier between cells and across tissues. On a genetic level, three APOE alleles are described, APOE2, APOE3 and APOE4. These alleles give rise to six APOE isoforms, which are differentially implicated in various diseases. In the peripheral system, APOE4 is linked to increased risk of atherosclerosis. In the CNS, the ability of APOE4 in clearing beta-amyloid is impaired, while APOE3 and APOE2 are more efficient in performing this task. The APOE4 genotype in particular has been linked to increased risk for developing Alzheimer's Disease.
Affinity-purified
Polyclonal
IgG
ELISA
Goat
Recombinant human Apolipoprotein E
Human
Human
Spin vial briefly before opening. Reconstitute in 100 µL sterile-filtered, ultrapure water. Centrifuge to remove any insoluble material. Store lyophilized antibody at 2-8°C. After reconstitution keep aliquots at -20°C to -80°C for higher stability. Avoid repetitive freeze/thaw cycles.
Lyophilized
Lyophilized from a solution containing 50 mM Tris, pH 7.5, 0.4 M NaCl, 0.01 M EDTA, 0.1% trehalose, 0.07% sodium azide.
ELISA: 0.1-1 µg/mL
ELISA (0.1-1 µg/mL). Other applications not tested as yet.
Unconjugated
Human. Species cross-reactivity not tested.
For research use only.
United States
12 months after date of receipt (unopened vial).
APOE;
25°C (ambient)