AM1-43 Nerve Terminal Staining Kit IIA
Our Nerve Terminal Staining Kit IIA contains our AM1-43 Nerve Terminal Dye and background reducer ADVASEP-7 for quenching extracellular dye fluorescence.
SKU: 81-8029
Ships: 1-5 business days
Product Details
Nerve terminal dyes have highly hydrophilic, cationically charged head groups at one end with lipophilic tails at the other end. They are virtually non-fluorescent in aqueous solution, but become intensely fluorescent in membranes. Following nerve stimulation, the dye molecules are internalized in newly formed endocytic vesicles. During exocytosis, the dyes are released from the vesicles along with neurotransmitters, causing a decrease in fluorescence signal. As a result, the change in fluorescent intensity reflects the amount of endocytosis/exocytosis or synaptic activity. Nerve Terminal Staining Kit IIA contains AM1-43 nerve terminal dye and ADVASEP-7 background reducing agent, a sulfonated cyclodextrin derivative for washing away or quenching extracellular dye fluorescence.
EM, ICC, IHC
Ex: 480 nm, Em: 598 nm (in membranes)
Store at 2°C to 8°C, protect from light.
Solid
For use in real-time imaging of live/intact cells and cells fixed after staining in formaldehyde.
For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
United States
Stable for 12 months after date of receipt.
Shipped at ambient temperature; protected from light