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Products: Primary Antibodies

Anti-VIP Antibody (L108/92)

NeuroMab Logo from NeuroMab

 Datasheet

PRODUCT OPTIONS

Brand Catalog # Option Volume Concentration Price
Brand
NeuroMab Logo
Catalog #
75-447
Option
Purified
Volume
100 µL
Concentration
1 mg/mL
Price
$275.00
Brand
NeuroMab Logo
Catalog #
73-447
Option
TC Supernatant
Volume
5 mL
Concentration
Lot dependent
Price
$275.00

Validation Images


Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG2b

Species Reactivity:

Human Rat

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

IHC

Target Description:

Vasoactive Intestinal Peptide (VIP) or PHM27 is encoded by the gene VIP and belongs to the glucagon family. VIP is a secreted peptide hormone and binds to the VIP receptors VIP R1 and VIP R2. Signaling through the receptors, VIP is involved diverse processes including vasodilation, regulation of blood pressure, stimulates myocardial contractility and neurotransmission. VIP is produced in many tissues including gut, pancreas, heart and brain. Diseases associated with this gene include Vipoma and Vasomotor Rhinitis.

Immunogen:

Fusion protein amino acids 81-152 (mature protein) of human VIP (also known as Vasoactive intestinal peptide and Vasoactive intestinal polypeptide, cleaved into Intestinal peptide PHI-42 / PHV-42 for Peptide histidine valine 42 and Intestinal peptide PHM-27 for Peptide histidine methioninamide 27 / Intestinal peptide PHI-27 for Peptide histidine isoleucinamide 27, accession number P01282)
Rat: 92% identity (66/72 amino acids identical)
Mouse: 90% identity (65/72 amino acids identical)
50% identity with PACAP

Protein Name(s):

VIP peptides [Cleaved into: Intestinal peptide PHV-42 (Peptide histidine valine 42); Intestinal peptide PHM-27 (Peptide histidine methioninamide 27); Vasoactive intestinal peptide (VIP) (Vasoactive intestinal polypeptide)]

Gene Name(s):

VIP

Antibody Registry ID:

Purified: AB_2651163
TC Supernatant: AB_ 2619640


Antibody Validation and Application Notes


This antibody has been validated using the following assays:
Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Immunohistochemistry:
This antibody shows the expected immunoperoxidase-diaminobenzidine / immunofluorescence staining pattern when used to stain brain sections.


Quality Control


The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it shows the expected immunoperoxidase-diaminobenzidine / immunofluorescence staining pattern when used to stain brain sections.