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Products: Primary Antibodies

Anti-TrpC4 Antibody (N77/15)

NeuroMab Logo from NeuroMab

 Datasheet

PRODUCT OPTIONS

Brand Catalog # Option Volume Concentration Price
Brand
NeuroMab Logo
Catalog #
75-119
Option
Purified
Volume
100 µL
Concentration
1 mg/mL
Price
$275.00
Brand
NeuroMab Logo
Catalog #
73-119
Option
TC Supernatant
Volume
5 mL
Concentration
Lot dependent
Price
$275.00

Validation Images


Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG2b

Species Reactivity:

Human Mouse Rat

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

ICC IHC IP WB

Target Description:

Short transient receptor potential channel 4 or TrpC4 is encoded by the gene TrpC4. TrpC4 belongs to the transient receptor family, a group of membrane bound ion channels that have a relatively non-selective permeability to cations, including sodium, calcium and magnesium. This protein is thought to have a role as a cell-cell contact-dependent endothelial calcium entry channel. Trpc4 is found in many tissues including CNS, placenta, heart, smooth muscle, testis, kidney and brain. Mutations in this gene areassociated with generalized epilepsy with photosensitivity.

Immunogen:

Synthetic peptide amino acids 930-947 (FKSEKVVVEDTVPIIPKE) of rat TrpC4 (also known as short transient receptor potential channel 4, Trp4, capacitative calcium entry channel 1 and CCE1, accession number O35119); Mouse: 100% identity (18/18 amino acids identical); Human: 100% identity (18/18 amino acids identical)

Cross Reactivity:

No cross-reactivity reported

Protein Name(s):

TrpC4

Gene Name(s):

Trpc4

Antibody Registry ID:

Purified: AB_2256454
TC Supernatant: AB_10698036


Antibody Validation and Application Notes


This antibody has been validated using the following assays:
Western Blot:

This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.

This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Immunohistochemistry:
This antibody shows the expected immunoperoxidase-diaminobenzidine / immunofluorescence staining pattern when used to stain brain sections.

Molecular Weight:

110 kDa


Quality Control


The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.