Products: Primary Antibodies
PRODUCT OPTIONS
| Catalog # | Option | Volume | Concentration | Price* | |
|---|---|---|---|---|---|
| Catalog # 75-029 |
Option Purified |
Volume 100 µL |
Concentration 1 mg/mL |
Price $269.00 |
|
| Catalog # 73-029 |
Option TC Supernatant |
Volume 5 mL |
Concentration Lot dependent |
Price $269.00 |
Validation Images
![Immunoblot against crude membrane fractions from whole mouse (MBM) or rat (RBM) brain and from human cerebellum [HBM(Cb)], cerebral cortex [HBM(Cx)] or hippocampus [HBM(H)] probed with K28/86 (left) or N52A/42 (right) TC supe.](http://cdn.shopify.com/s/files/1/0014/8806/0475/products/validation-image-73-029-k28-86-wb-3.jpg?v=1549987714)
Overview
NeuroMab
Monoclonal
Mouse
IgG1
Human Mouse Rat Xenopus Zebrafish
IP WB
Fusion protein amino acids 77-299 of human PSD-95/SAP90
Rat: 100% identity (223/223 amino acids identical)
Mouse: 99% identity (221/223 amino acids identical)
65-80% identity with DLG1/SAP97, DLG2/Chapsyn-110 and DLG3/SAP102
Exhibits cross-reactivity against recombinant Chapsyn-110, SAP97 and SAP102
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg) Disks large homolog 2 (Channel-associated protein of synapse-110) (Chapsyn-110) (Postsynaptic density protein PSD-93) Disks large homolog 3 (Neuroendocrine-DLG) (Synapse-associated protein 102) (SAP-102) (SAP102) (XLMR) Disks large homolog 4 (Postsynaptic density protein 95) (PSD-95) (Synapse-associated protein 90) (SAP-90) (SAP90)
DLG1 DLG2 DLG3 KIAA1232 DLG4 PSD95
Purified: AB_10673115
TC Supernatant: AB_10698179
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody recognizes a single immunoreactive band of expected molecularweight when used to probe brain lysate.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
95-110 kDa(varies with cell background due to phosphorylation)
Quality Control
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
Citations and References
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- Chen X, Nelson CD, Li X, Winters CA, Azzam R, Sousa AA, Leapman RD, Gainer H, Sheng M, Reese TS.. (2011), 'PSD-95 is required to sustain the molecular organization of the postsynaptic density. .' Journal of Neuroscience. 10.1523/JNEUROSCI.5968-10.2011. " "
- Sheets L, Trapani JG, Mo W, Obholzer N, Nicolson T.. (2011), 'Ribeye is required for presynaptic Ca(V)1.3a channel localization and afferent innervation of sensory hair cells. .' Development. 10.1242/dev.059451. " "
- Micheva KD, Busse B, Weiler NC, O'Rourke N, Smith SJ.. (2010), 'Single-synapse analysis of a diverse synapse population: proteomic imaging methods and markers. .' Neuron. 10.1016/j.neuron.2010.09.024. "
- Sharma N, Deppmann CD, Harrington AW, St Hillaire C, Chen ZY, Lee FS, Ginty DD.. (2010), 'Long-distance control of synapse assembly by target-derived NGF..' Neuron. 10.1016/j.neuron.2010.07.018.
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- Yamagata M, Sanes JR.. (2009), 'Synaptic localization and function of Sidekick recognition molecules require MAGI scaffolding proteins. .' Journal of Neuroscience. 10.1523/JNEUROSCI.6319-09.2010. "
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- Ross BS, Conroy WG.. (2008), 'Capabilities of neurexins in the chick ciliary ganglion. .' Developmental Neurobiology. 10.1002/dneu.20598. "