Products: Primary Antibodies

Anti-Kv7.1/KCNQ1 K+ channel Antibody (N37A/10)

NeuroMab Logo from NeuroMab

 Datasheet

PRODUCT OPTIONS

Brand Catalog # Option Volume Concentration Price
Brand
NeuroMab Logo
Catalog #
75-081
Option
Purified
Volume
100 µL
Concentration
1 mg/mL
Price
$275.00
Brand
NeuroMab Logo
Catalog #
73-081
Option
TC Supernatant
Volume
5 mL
Concentration
Lot dependent
Price
$275.00

Validation Images


Product Details

Antibody Type:

Monoclonal

Host Species:

Mouse

Antibody Isotype:

IgG1

Species Reactivity:

Human Mouse Rat

Applications:
WB Western Blot
IHC Immunohistochemistry
ICC Immunocytochemistry
IP Immunoprecipitation
AT Array Tomography
EM Electron Microscopy
CHIP Chromatin Immunoprecipitation
DB Dot Blot

IHC IP WB

Target Description:

Potassium voltage-gated channel subfamily Q member 1 is encoded by the gene KCNQ1. KCNQ1 is a member of the potassium channel family, KQT (TC 1.A.1.15) subfamily, Kv7.1/KCNQ1 sub-subfamily. KCNQ1 is a voltage-gated potassium channel that is required for the repolarization phase of the cardiac action potential. KCNQ1 can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. KCNQ1 is expressed in the heart, pancreas, kidney, prostate, small intestine, and peripheral blood leukocytes. Diseases associated with KCNQ1 include Long QT Syndrome1, Jervell and Lange-Nielsen Syndrome, atrial fibrillation familial 3, short QT syndrome 2, and atrial fibrillation.

Immunogen:

Fusion protein amino acids 2-101 of human KCNQ1(Kv7.1, KvLQT1, accession number P51787); Rat: 72% identity (71/98 amino acids identical); Mouse: 63% identity (62/98 amino acids identical)

Cross Reactivity:

No cross-reactivity reported

Protein Name(s):

Kv7.1/KCNQ1 K+ channel

Gene Name(s):

KCNQ1 KCNA8 KCNA9 KVLQT1

Antibody Registry ID:

Purified: AB_2131682
TC Supernatant: AB_10675286


Antibody Validation and Application Notes


This antibody has been validated using the following assays:
Western Blot:

This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.

Immunocytochemistry:

This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.

Molecular Weight:

75 kDa


Quality Control


The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.

Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.