Human Mouse Rat
IHC IP WB
Potassium voltage-gated channel subfamily Q member 1 is encoded by the gene KCNQ1. KCNQ1 is a member of the potassium channel family, KQT (TC 1.A.1.15) subfamily, Kv7.1/KCNQ1 sub-subfamily. KCNQ1 is a voltage-gated potassium channel that is required for the repolarization phase of the cardiac action potential. KCNQ1 can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. KCNQ1 is expressed in the heart, pancreas, kidney, prostate, small intestine, and peripheral blood leukocytes. Diseases associated with KCNQ1 include Long QT Syndrome1, Jervell and Lange-Nielsen Syndrome, atrial fibrillation familial 3, short QT syndrome 2, and atrial fibrillation.
Fusion protein amino acids 2-101 of human KCNQ1(Kv7.1, KvLQT1, accession number P51787); Rat: 72% identity (71/98 amino acids identical); Mouse: 63% identity (62/98 amino acids identical)
No cross-reactivity reported
Kv7.1/KCNQ1 K+ channel
KCNQ1 KCNA8 KCNA9 KVLQT1
TC Supernatant: AB_10675286
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe lysate from COS cells overexpressing target.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it shows the expected staining pattern when used to stain COS cells overexpressing target.