Human Mouse Rat
AT ICC IHC WB
Brain-specific angiogenesis inhibitor 1-associated protein 2 or IRSp53/BAIAP2 is encoded by the gene BAIAP2 and is a MAGUK (membrane-associted guanylase kinase homolog) family. BAIAP2 is an adaptor protein which links G-proteins in the membrane to cytoplasmic proteins and is involved in cell processes including regulation of the actin cytoskeleton, neurite growth and the promotion of filipodia formation. Multiple isoforms of BAIAP2 exist with differential tissue expression. Diseases associated with BAIAP2 include Dentatorubral-Pallidoluysian Atrophy and Attention Deficit-Hyperactivity Disorder.
Fusion protein amino acids 1-250 (N-terminus) of human BAIAP2 (also known as Brain-specific angiogenesis inhibitor 1-associated protein 2, BAI-associated protein 2, BAI1-associated protein 2, Insulin receptor substrate p53/p58, Insulin receptor substrate protein of 53 kDa, Insulin receptor tyrosine kinase 53 kDa substrate, Insulin receptor tyrosine kinase substrate protein p53, Fas ligand-associated factor 3, BAP2, IRS-58, IRSp53/58, IRSp53 and FLAF3, accession number Q9UQB8)
Mouse: 97% identity (243/250 amino acids identical)
Rat: 97% identity (242/250 amino acids identical)
50% identity with BAIAP2L1
Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI-associated protein 2) (BAI1-associated protein 2) (Protein BAP2) (Fas ligand-associated factor 3) (FLAF3) (Insulin receptor substrate p53/p58) (IRS-58) (IRSp53/58) (Insulin receptor substrate protein of 53 kDa) (IRSp53) (Insulin receptor substrate p53)
TC Supernatant: AB_2619741
Antibody Validation and Application Notes
This antibody has been validated using the following assays:
This antibody recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
This antibody shows the expected staining pattern when used to stain COS cells overexpressing target.
The following quality control assay is performed on each new lot of this antibody to ensure it meets designated performance requirements.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.