Adult rat brain striatum and globus pallidus immunohistochemistry.
Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) (mVGAT) (mVIAAT)
The Vesicular GABA Amino Acid Transporter (VGAT) is responsible for transport of the inhibitory neurotransmitter into synaptic vesicles(McIntire et al., 1997). The VGAT protein (also known as the Vesicular Inhibitory Amino Aid Transporter or VIAAT) is expressed in synaptic vesicles of both glycine and GABAergic synapses throughout the CNS (Chaudhry et al., 1998). Expression of the VGAT protein changes during development and also in response to patterns of neuronal activity (De et al., 2005).
ICC, IHC, WB
Slc32a1 Vgat Viaat
Fusion protein amino acids 1-133 (cytoplasmic N-terminus) of mouse VGAT (also known as GABA and glycine transporter, Vesicular inhibitory amino acid transporter, Vesicular GABA transporter, Solute carrier family 32 member 1, VIAAT and SLC32A1, accession number O35633); Rat: 99% identity (132/133 amino acids identical); Human: 96% identity (128/134 amino acids identical)
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.