Disks large-associated protein 3,SAP90/PSD-95-Associated Protein 3 or SAPAP3 is encoded by the gene DLGAP3 and is a member of the SAPAP or DLGAP family of proteins. SAPAP3 acts as a scaffold protein and is involved with glutamate receptor signaling. SAPAP3 is highly expressed in the central and peripheral nervous system. Within the cell, SAPAP3 is found at the postsynaptic density. Diseases associated with DLGAP3 include Trichotillomania and Body Dysmorphic Disorder.
ICC, IHC, WB
Fusion protein amino acids 790-977 (C-terminus) of mouse SAPAP3 (also known as Disks large- associated protein 3, PSD-95/SAP90-binding protein 3, SAP90/PSD-95 associated protein 3, Dlgap3 and Dap3, accession number Q6PFD5); Rat: 100% identity (188/188 amino acids identical); Human: 99% identity (186/188 amino acids identical); >60% identity with SAPAP2/DLGAP2 and other SAPAP/DLGAP proteins
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from opening
SAPAP3, Disks large- associated protein 3, PSD 95/SAP90-binding protein 3, SAP90/PSD-95 associated protein
UniProt (Immunogen Species): Q6PFD5
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