Pannexin 2 is encoded by the gene PANX2. PANX2 is a member of the pannexin family. PANX2 combines with pannexin 1 to form cell type-specific gap junctions with distinct properties. PANX2 is expressed in the eye, thyroid, prostate, kidney, liver, and central nervous system. Diseases associated with PANX2 include Oculodentodigital Dysplasia and Chronic Closed-Angle Glaucoma.
Fusion protein amino acids 11-664 (all but first 10 amino acids, encompassing extracellular and cytoplasmic domains) of rat Pannexin-2(also known as Panx2 and Px2, accession number P60571); Mouse: 98% identity (645/657 amino acids identical); Human: 91% identity (564/615 amino acids identical); Less than 30% identity with Pannexin-1 and Pannexin-3
Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Does not cross-react with Pannexin-1 or Pannexin-3
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.