Anti-Pannexin-2 Antibody (N121A/1)

Name: Anti-Pannexin-2 Antibody
Brand: NeuroMab
SKU: 75-212
Price: 295.0 USD
Availability: InStock

from NeuroMab Datasheet

1 Citation

Product Type

Primary Antibody

Species Reactivity

Rat

Clone

N121A/1

Applications

IHC, WB

Host Species

Mouse

Format

Purified

Gene Name

Panx2 Px2

Molecular Weight

70 kDa

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Adult rat hippocampus immunohistochemistry.

Volume: 100 µL

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$295

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Target

Pannexin-2

Target Description

Pannexin 2 is encoded by the gene PANX2. PANX2 is a member of the pannexin family. PANX2 combines with pannexin 1 to form cell type-specific gap junctions with distinct properties. PANX2 is expressed in the eye, thyroid, prostate, kidney, liver, and central nervous system. Diseases associated with PANX2 include Oculodentodigital Dysplasia and Chronic Closed-Angle Glaucoma.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N121A/1

Isotype

IgG2a

Applications

IHC, WB

Host Species

Mouse

Gene Name

Panx2 Px2

Molecular Weight

70 kDa

Antigen

Fusion protein amino acids 11-664 (all but first 10 amino acids, encompassing extracellular and cytoplasmic domains) of rat Pannexin-2(also known as Panx2 and Px2, accession number P60571); Mouse: 98% identity (645/657 amino acids identical); Human: 91% identity (564/615 amino acids identical); Less than 30% identity with Pannexin-1 and Pannexin-3

Species Reactivity

Rat

Antibody Registry ID

AB_10673510

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Specificity

Does not cross-react with Pannexin-1 or Pannexin-3

Quality Control

Each new lot of this antibody is tested to confirm that it shows the expected immunoperoxidase-diaminobenzidine / immunofluorescence staining pattern when used to stain brain sections.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

Pannexin-2

UniProt Details

UniProt (Human): Q96RD6
UniProt (Immunogen Species): P60571

Le Vasseur M, Lelowski J, Bechberger JF, Sin WC, Naus CC. (2014), 'Pannexin 2 protein expression is not restricted to the CNS..' Frontiers in Neuroscience. 10.3389/fncel.2014.00392.

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Anti-Pannexin-2 Antibody (N121A/1)

Anti-Pannexin-2 Antibody
SKU: 75-212

Bulk Order Anti-Pannexin-2 Antibody

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Anti-Pannexin-2 Antibody (N121A/1)

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Bulk Order Anti-Pannexin-2 Antibody

Product Details

Anti-Pannexin-2 Antibody
SKU: 75-212