Anti-Kv2.1 K+ Channel (External) Antibody (K39/25)
Primary Antibody
Human, Mouse, Rat
K39/25
ICC, IHC, WB
Mouse
Purified by Protein A chromatography
KCNB1
105-125 kDa (varies with cell background due to phosphorylation)
Surface immunofluorescence (no detergent permeabilization) of cultured rat hippocampal neuron transfected with HA-tagged Kv2.1 plasmid. Red = K39/25. Scale bar = 20 m. Reproduced from 2000 Lim et al Neuron (PMID 10719893).
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- David JP, Stas JI, Schmitt N, Bocksteins E. (2015), 'Auxiliary KCNE subunits modulate both homotetrameric Kv2.1 and heterotetrameric Kv2.1/Kv6.4 channels..' Scientific Reports. 10.1038/srep12813.
- Nieves-Cintrón M, Nystoriak MA, Prada MP, Johnson K, Fayer W, Dell''Acqua ML, Scott JD, Navedo MF. (2015), 'Selective down-regulation of KV2.1 function contributes to enhanced arterial tone during diabetes..' The Journal of Biological Chemistry. 10.1074/jbc.M114.622811.
- Zhao X, Kuja-Panula J, Sundvik M, Chen YC, Aho V, Peltola MA, Porkka-Heiskanen T, Panula P, Rauvala H. (2014), 'Amigo adhesion protein regulates development of neural circuits in zebrafish brain..' The Journal of Biological Chemistry. 10.1074/jbc.M113.545582.
- Battonyai I, Krajcs N, Serfőző Z, Kiss T, Elekes K. (2014), 'Potassium channels in the central nervous system of the snail, Helix pomatia: localization and functional characterization..' Neuroscience. 10.1016/j.neuroscience.2014.03.006.
- Kirizs T, Kerti-Szigeti K, Lorincz A, Nusser Z. (2014), 'Distinct axo-somato-dendritic distributions of three potassium channels in CA1 hippocampal pyramidal cells..' European Journal of Neuroscience. 10.1111/ejn.12526.
- Jensen CS, Watanabe S, Rasmussen HB, Schmitt N, Olesen SP, Frost NA, Blanpied TA, Misonou H. (2014), 'Specific sorting and post-Golgi trafficking of dendritic potassium channels in living neurons..' The Journal of Biological Chemistry. 10.1074/jbc.M113.534495.
- Lopez-Izquierdo A, Pereira RO, Wende AR, Punske BB, Abel ED, Tristani-Firouzi M. (2014), 'The absence of insulin signaling in the heart induces changes in potassium channel expression and ventricular repolarization..' American Journal of Physiology-Heart and Circulatory Physiology. 10.1152/ajpheart.00849.2013.
- Marionneau C, Carrasquillo Y, Norris AJ, Townsend RR, Isom LL, Link AJ, Nerbonne JM. (2012), 'The sodium channel accessory subunit Navβ1 regulates neuronal excitability through modulation of repolarizing voltage-gated K⁺ channels..' Journal of Neuroscience. 10.1523/JNEUROSCI.6450-11.2012.
- Peltola MA, Kuja-Panula J, Lauri SE, Taira T, Rauvala H. (2011), 'AMIGO is an auxiliary subunit of the Kv2.1 potassium channel..' EMBO Reports. 10.1038/embor.2011.204.
- Plant LD, Dowdell EJ, Dementieva IS, Marks JD, Goldstein SA. (2011), 'SUMO modification of cell surface Kv2.1 potassium channels regulates the activity of rat hippocampal neurons..' The Journal of General Physiology. 10.1085/jgp.201110604.
- Cheng L, Yung A, Covarrubias M, Radice GL. (2011), 'Cortactin is required for N-cadherin regulation of Kv1.5 channel function..' The Journal of Biological Chemistry. 10.1074/jbc.M111.218560.
- Nataraj K, Le Roux N, Nahmani M, Lefort S, Turrigiano G. (2010), 'Visual deprivation suppresses L5 pyramidal neuron excitability by preventing the induction of intrinsic plasticity..' Neuron. 10.1016/j.neuron.2010.09.033.
- Bocksteins E, Labro AJ, Mayeur E, Bruyns T, Timmermans JP, Adriaensen D, Snyders DJ. (2009), 'Conserved negative charges in the N-terminal tetramerization domain mediate efficient assembly of Kv2.1 and Kv2.1/Kv6.4 channels..' The Journal of Biological Chemistry. 10.1074/jbc.M109.039479.
- Mohapatra DP, Siino DF, Trimmer JS. (2008), 'Interdomain cytoplasmic interactions govern the intracellular trafficking, gating, and modulation of the Kv2.1 channel..' Journal of Neuroscience. 10.1523/JNEUROSCI.0186-08.2008.