Anti-Kv2.1 K+ Channel (External) Antibody (K39/25)

Our Anti-Kv2.1 K+ channel (external) mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K39/25. It detects human, mouse, and rat Kv2.1 K+ channel (external), and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

SKU: 75-159

Volume: 100 µL
1-2 business days
Sale price$319

Product Specific References for Applications and Species

Immunocytochemistry: Human
PMID Dilution Publication
302897501:100David, J.P., et al. 2019. Deletion in mice of X-linked, Brugada syndrome- and atrial fibrillation-associated Kcne5 augments ventricular KV currents and predisposes to ventricular arrhythmia. FESEB Journal, 2537-2552.
262427571:100David, J.P., et al. 2015. Auxiliary KCNE subunits modulate both homotetrameric Kv2.1 and heterotetrameric Kv2.1/Kv6.4 channels.. Scientific Reports, 12813.
197175581:50Bocksteins, E., et al. 2009. Conserved negative charges in the N-terminal tetramerization domain mediate efficient assembly of Kv2.1 and Kv2.1/Kv6.4 channels.. The Journal of Biological Chemistry, 31625-31634.
18463252not listedMohapatra, D.P., et al. 2008. Interdomain cytoplasmic interactions govern the intracellular trafficking, gating, and modulation of the Kv2.1 channel.. Journal of Neuroscience, 4982-4994.
Immunocytochemistry: Mouse
PMID Dilution Publication
25670860not listedNieves-Cintrón, M., et al. 2015. Selective down-regulation of KV2.1 function contributes to enhanced arterial tone during diabetes.. The Journal of Biological Chemistry, 7918-7929.
Immunohistochemistry: Rat
PMID Dilution Publication
246065841:300Kirizs, T., et al. 2014. Distinct axo-somato-dendritic distributions of three potassium channels in CA1 hippocampal pyramidal cells.. European Journal of Neuroscience, 1771-1783.
210928635ug/mlNataraj, K., et al. 2010. Visual deprivation suppresses L5 pyramidal neuron excitability by preventing the induction of intrinsic plasticity.. Neuron, 750-762.
Immunohistochemistry: Snail
PMID Dilution Publication
246317131:500Battonyai, I., et al. 2014. Potassium channels in the central nervous system of the snail, Helix pomatia: localization and functional characterization.. Neuroscience, 87-101.
Immunoprecipitation: Mouse
PMID Dilution Publication
220568184ug/mlPeltola, M.A., et al. 2011. AMIGO is an auxiliary subunit of the Kv2.1 potassium channel.. EMBO Reports, 1293-1299.
Immunoprecipitation: Rat
PMID Dilution Publication
245699932ug/mlJensen, C.S., et al. 2014. Specific sorting and post-Golgi trafficking of dendritic potassium channels in living neurons.. The Journal of Biological Chemistry, 10566-10581.
Immunoprecipitation: Zebrafish
PMID Dilution Publication
249040582ug/mlZhao, X., et al. 2014. Amigo adhesion protein regulates development of neural circuits in zebrafish brain.. The Journal of Biological Chemistry, 19958-19975.
Western Blot: Mouse
PMID Dilution Publication
3313220310ug/mlHawkins, N.A., et al. 2021. Epilepsy and neurobehavioral abnormalities in mice with a dominant-negative KCNB1 pathogenic variant. Neurobiology Disorders, 105141.
268901391:500Frazzini, V., et al. 2016. Altered Kv2.1 functioning promotes increased excitability in hippocampal neurons of an Alzheimer''s disease mouse model.. Cell Death & Disease, e2100.

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