Anti-IRSp53/BAIAP2 Antibody (L117/1)

Name: Anti-IRSp53/BAIAP2 Antibody
Brand: NeuroMab
SKU: 75-449
Price: 295.0 USD
Availability: InStock

from NeuroMab Datasheet

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Clonality

Monoclonal

Applications

AT, ICC, IHC, WB

Host Species

Mouse

Gene Name

BAIAP2

Molecular Weight

50-60 kDa

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Array tomography immunofluorescence of an LRWhite-embedded 70 nm section from adult mouse cortex layer 5 with L117/1 (red), rabbit mAb PSD-95 (Cell Signaling

Adult rat hippocampus immunohistochemistry.

Array tomography immunofluorescence of an LRWhite-embedded 70 nm section from adult mouse cortex layer 5 with L117/1 (red), rabbit mAb PSD-95 (Cell Signaling #3450, green) and DAPI (blue), where L117/1 colocalizes with some PSD-95 puncta. Image courtesy of Kristina Micheva (Stanford)..

Product Details

Target

Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI-associated protein 2) (BAI1-associated protein 2) (Protein BAP2) (Fas ligand-associated factor 3) (FLAF3) (Insulin receptor substrate p53/p58) (IRS-58) (IRSp53/58) (Insulin receptor substrate protein of 53 kDa) (IRSp53) (Insulin receptor substrate p53)

Target Description

Brain-specific angiogenesis inhibitor 1-associated protein 2 or IRSp53/BAIAP2 is encoded by the gene BAIAP2 and is a MAGUK (membrane-associted guanylase kinase homolog) family. BAIAP2 is an adaptor protein which links G-proteins in the membrane to cytoplasmic proteins and is involved in cell processes including regulation of the actin cytoskeleton, neurite growth and the promotion of filipodia formation. Multiple isoforms of BAIAP2 exist with differential tissue expression. Diseases associated with BAIAP2 include Dentatorubral-Pallidoluysian Atrophy and Attention Deficit-Hyperactivity Disorder.

Format

Purified

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

L117/1

Isotype

IgG1

Applications

AT, ICC, IHC, WB

Host Species

Mouse

Gene Name

BAIAP2

Molecular Weight

50-60 kDa

Antigen

Fusion protein amino acids 1-250 (N-terminus) of human BAIAP2 (also known as Brain-specific angiogenesis inhibitor 1-associated protein 2, BAI-associated protein 2, BAI1-associated protein 2, Insulin receptor substrate p53/p58, Insulin receptor substrate protein of 53 kDa, Insulin receptor tyrosine kinase 53 kDa substrate, Insulin receptor tyrosine kinase substrate protein p53, Fas ligand-associated factor 3, BAP2, IRS-58, IRSp53/58, IRSp53 and FLAF3, accession number Q9UQB8); Mouse: 97% identity (243/250 amino acids identical); Rat: 97% identity (242/250 amino acids identical); 50% identity with BAIAP2L1

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2651164

Storage

Store at ≤ -20 C for long term storage. For short term storage, store at 2-8 C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Buffer

10mM Tris, 50mM Sodium Chloride, 0.065 % Sodium Azide pH 7.4

Conjugate

Unconjugated

Quality Control

Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used to probe brain lysate.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from opening

Synonyms

UniProt Details

UniProt (Human): Q9UQB8
UniProt (Immunogen Species): Q9UQB8

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Anti-IRSp53/BAIAP2 Antibody (L117/1)

Anti-IRSp53/BAIAP2 Antibody
SKU: 75-449

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Anti-IRSp53/BAIAP2 Antibody (L117/1)

Anti-IRSp53/BAIAP2 Antibody SKU: 75-449

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Anti-IRSp53/BAIAP2 Antibody
SKU: 75-449