Anti-Centromere Protein Antibody

Our Anti-Centromere proteins human polyclonal primary antibody from Antibodies Incorporated is produced in-house. It detects Centromere proteins, and is purified by Protein A chromatography. It is great for use in ICC.

SKU: 15-235

Volume: 1 mL
Sale price$170

Product Specific References for Applications and Species

ELISA: Human
PMID Dilution Publication
316827301:100van der Bijl, N., et al. 2019. Mutations in the stromal antigen 3 (STAG3) gene cause male infertility due to meiotic arrest. Human Reproduction, 2112-2119.
Immunocytochemistry: Human
PMID Dilution Publication
374849141:200Didaskalou, S, et al. 2023. HURP Localization in Metaphase is the Result of a Multi-step Process Requiring its Phosphorylation at Ser627 Residue. Frontiers in cell and developmental biology, 981425.
364146421:1000Zadra, I., et al. 2022. Chromosome Segregation Fidelity Requires Microtubule Polyglutamylation By The Cancer Downregulated Enzyme TTLL411. Nature Communications, 7147.
363506971:500Janczyk, P.Ł, et al. 2022. Aurora A Phosphorylates Ndel1 To Reduce The Levels Of Mad1 And NuMA At Spindle Poles. Molecular Biology Of The Cell, .
36322655not listedVillarroya-Beltri, C., et al. 2022. Biallelic Germline Mutations In MAD1L1 Induce A Syndrome Of Aneuploidy With High Tumor Susceptibility. Science Advances, eabq5914.
35858625not listedPalmerola, K.L., et al. 2022. Replication Stress Impairs Chromosome Segregation and Preimplantation Development in Human Embryos. Cell, 2988-3007.
358424281:2000De Marco Zompit, M., et al. 2022. The CIP2A-TOPBP1 complex safeguards chromosomal stability during mitosis. Nature Communications, 4143.
357761321:300Abad, M.A., et al. 2022. Mechanistic Basis for Sgo1-Mediated Centromere Localization and Function of the CPC. The Journal of Cell Biology, .
356007661:40Hong, J., et al. 2022. Ginsenoside Rg1 suppresses cancer cell proliferation through perturbing mitotic progression. Journal of Ginseng Research, 481-488.
354837401:600Herman, J.A., et al. 2022. Functional dissection of human mitotic genes using CRISPR–Cas9 tiling screens. Genes and Development, 495-510.
347977171:250Solon, A.L., et al. 2021. Kinesin-binding protein remodels the kinesin motor to prevent microtubule binding. Science Advances, .
34166371not listedHagihara, Y., et al. 2021. Tet1 regulates epigenetic remodeling of the pericentromeric heterochromatin and chromocenter organization in DNA hypomethylated cells. PLOS Genetics, e1009646.
34048564not listedWoodworth, M.A., et al. 2021. Multiplexed single-cell profiling of chromatin states at genomic loci by expansion microscopy. Nucleic Acids Research, e82.
34048314not listedCheng, A., et al. 2021. Energy restriction causes metaphase delay and chromosome mis-segregation in cancer cells. Cell Cycle, 1195-1208.
339810161:200Xu, X., et al. 2021. Targeting the actin/tropomyosin cytoskeleton in epithelial ovarian cancer reveals multiple mechanisms of synergy with anti-microtubule agents. British Journal of Cancer, 265-276.
336192541:250Marquis, C., et al. 2021. Chromosomally unstable tumor cells specifically require KIF18A for proliferation. Nature Communications, 1213.
333778661:600Herman, J.A., et al. 2020. chTOG is a conserved mitotic error correction factor. Elife, e61773.
331807671:100Gil-Fernández, A., et al. 2020. Meiosis reveals the early steps in the evolution of a neo-XY sex chromosome pair in the African pygmy mouse Mus minutoides. PLOS Genetics, e1008959.
320017121:40Kim, S., et al. 2020. PRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation. Nature Communications, 612.
315704991:300Abad, M.A., et al. 2019. Borealin–nucleosome interaction secures chromosome association of the chromosomal passenger complex. Journal of Cell Biology, 3912-3925.
314205361:1000Han, T., et al. 2019. Interplay between c-Src and the APC/C co-activator Cdh1 regulates mammary tumorigenesis. Nature Communications, 3716.
307098522.5ug/mlMalaby, H.L., et al. 2019. Kinesin-binding protein ensures accurate chromosome segregation by buffering KIF18A and KIF15. Journal of Cell Biology, 1218-1234.
30368549not listedYang, Y., et al. 2019. NudCL2 is an Hsp90 cochaperone to regulate sister chromatid cohesion by stabilizing cohesin subunits. Cellular and Molecular Life Sciences, 381-395.
30143891not listedSun, M., et al. 2018. Condensin controls mitotic chromosome stiffness and stability without forming a structurally contiguous scaffold. Chromosome Research, 277-295.
Immunocytochemistry: Mouse
PMID Dilution Publication
364291341:5Sánchez-Sáez, F., et al. 2022. The Oocyte-Specific Linker Histone H1FoOO Is Not Essential For Mouse Oogenesis And Fertility. Cells, .
363542071:50Chen, L., et al. 2022. Septin 9 Controls Ccnb1 Stabilization Via APC/CCDC20 During Meiotic Metaphase I/Anaphase I Transition In Mouse Oocytes. Cell Proliferation, e13359.
358050971:100Petrusová, J., et al. 2022. Focal adhesion protein Vinculin is required for proper meiotic progression during mouse spermatogenesis. Cells, 2013.
354470831:500Mitrentsi, I., et al. 2022. Heterochromatic repeat clustering imposes a physical barrier on homologous recombination to prevent chromosomal translocations. Molecular cell, 2132-2147.
353207531:500Chardon, F., et al. 2022. CENP-B-mediated DNA loops regulate activity and stability of human centromeres. Molecular cell, 1751-1767.
343146791:500Chatzidaki, E.E., et al. 2021. Ovulation suppression protects against chromosomal abnormalities in mouse eggs at advanced maternal age. Current Biology, 4038-4051.
326771481:200Hsieh, C., et al. 2020. MIWI prevents aneuploidy during meiosis by cleaving excess satellite RNA. EMBO Journal, e103614.
32642764not listedMukaj, A., et al. 2020. Prdm9 Intersubspecific Interactions in Hybrid Male Sterility of House Mouse. Molecular Biology Evolution, 3423-3438.
326342441:25Balboula, A.Z., et al. 2020. Vitrification-induced activation of lysosomal cathepsin B perturbs spindle assembly checkpoint function in mouse oocytes. Molecular Human Reproduction, 689-701.
325746751:50Dong, F., et al. 2020. Chronic Cadmium Exposure Causes Oocyte Meiotic Arrest by Disrupting Spindle Assembly Checkpoint and Maturation Promoting Factor. Reproductive Toxicology, 141-149.
320512541:5McNicoll, F., et al. 2020. Meiotic sex chromosome cohesion and autosomal synapsis are supported by Esco2. Life Science Alliance, e201900564.
31895940not listedLovejoy, C.A., et al. 2020. ATRX affects the repair of telomeric DSBs by promoting cohesion and a DAXX-dependent activity. PLoS Biology, e3000594.
317509581:500Dumont, M., et al. 2020. Human chromosome‐specific aneuploidy is influenced by DNA‐dependent centromeric features. EMBO Journal, e102924.
31495584not listedVargas-Hurtado, D., et al. 2019. Differences in mitotic spindle architecture in mammalian neural stem cells influence mitotic accuracy during brain development. Current Biology, 2993-3005.
314928851:200Zhao, B., et al. 2019. ARID1A promotes genomic stability through protecting telomere cohesion. Nature Communications, 4067.
314372131:5Gómez-H, L., et al. 2019. The PSMA8 subunit of the spermatoproteasome is essential for proper meiotic exit and mouse fertility. PLOS Genetics, e1008316.
Immunohistochemistry: Fish (Lamprey)
PMID Dilution Publication
368368581:100Matveevsky, S., et al. 2023. The First Analysis of Synaptonemal Complexes in Jawless Vertebrates: Chromosome Synapsis and Transcription Reactivation at Meiotic Prophase I in the Lamprey …. Life, 501.
Immunohistochemistry: Gecko
PMID Dilution Publication
353884151:50Dedukh, D., et al. 2022. Premeiotic endoreplication is essential for obligate parthenogenesis in geckos. Development, .
Immunohistochemistry: Horse
PMID Dilution Publication
331395831:250Rizzo, M., et al. 2020. The horse as a natural model to study reproductive aging-induced aneuploidy and weakened centromeric cohesion in oocytes. Aging, 22220-22232.
Immunohistochemistry: Human
PMID Dilution Publication
35559990not listedKitasaka, H., et al. 2022. Oocyte cytoplasmic diameter of≥ 130 μm can be used to determine human giant oocytes. F&S Science, 10-17.
Immunohistochemistry: Mouse
PMID Dilution Publication
345734161:100Gil-Fernández, A., et al. 2021. Meiotic Behavior of Achiasmate Sex Chromosomes in the African Pygmy Mouse Mus mattheyi Offers New Insights into the Evolution of Sex Chromosome Pairing and …. Genes , 1434.
336448941:50Mengoli, V., et al. 2021. Deprotection of centromeric cohesin at meiosis II requires APC/C activity but not kinetochore tension. EMBO Journal, e106812.
33406415not listedCheng, E.C., et al. 2021. The essential function of SETDB1 in homologous chromosome pairing and synapsis during meiosis. Cell Reports, 108575.
325553481:1000Bondarieva, A., et al. 2020. Proline-rich Protein PRR19 Functions With Cyclin-Like CNTD1 to Promote Meiotic Crossing Over in Mouse. Nature Communications, 3101.
306744171:50Ehrmann, I., et al. 2019. An ancient germ cell-specific RNA-binding protein protects the germline from cryptic splice site poisoning. Elife, e39304.
Western Blot: Human
PMID Dilution Publication
347316372ug/mlSalinas-Luypaert, C., et al. 2021. Gene replacement strategies validate the use of functional tags on centromeric chromatin and invalidate an essential role for CENP-AK124ub. Cell Reports, 109924.
313488891:500Logsdon, G.A., et al. 2019. Human artificial chromosomes that bypass centromeric DNA. Cell, 624-639.
306355862ug/mlBarra, V., et al. 2019. Phosphorylation of CENP-A on serine 7 does not control centromere function. Nature Communications, 175.
Additional Publications: Unspecified
PMID Publication
35333353Zhong, Y., et al. 2022. XBP1 variant 1 promotes mitosis of cancer cells involving upregulation of the polyglutamylase TTLL6. Human Molecular Genetics, 2639-2654.
35194187Merchut-Maya, J.M., et al. 2022. Human cytomegalovirus hijacks host stress response fueling replication stress and genome instability. Cell Death and Differentiation, 1639-1653.
35146845Li, X., et al. 2022. Resveratrol protects renal damages induced by periodontitis via preventing mitochondrial dysfunction in rats. Oral Diseases, .
33825031Gil-Fernández, A., et al. 2021. Sex differences in the meiotic behavior of an XX sex chromosome pair in males and females of the mole vole Ellobius tancrei: turning an X into a Y chromosome?. Chromasoma, 113-131.
31940063Mihola, O.,, et al. 2020. Copy-number variation introduced by long transgenes compromises mouse male fertility independently of pachytene checkpoints. Chromasoma, 69-82.
30826871Ribagorda, M., et al. 2019. Meiotic behavior of a complex hexavalent in heterozygous mice for Robertsonian translocations: insights for synapsis dynamics. Chromasoma, 149-163.
30375749Hu, H., et al. 2019. Visualization of Genomic Loci in Living Cells with BiFC‐TALE. Current Protocols in Cellular Biology, e78.
30095409Frith, T.J., et al. 2018. Human axial progenitors generate trunk neural crest cells in vitro. Elife, e35786.
29805078Cánovas, B., et al. 2018. Targeting p38α increases DNA damage, chromosome instability, and the anti-tumoral response to taxanes in breast cancer cells. Cancer Cell, 1094-1110.
29718399Wu, X., et al. 2018. A CRISPR/molecular beacon hybrid system for live-cell genomic imaging. Nucleic Acids Research, e80.
29670078Montero, J.J., et al. 2018. TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin. Nature Communications, 1548.
29632243Berto, A., et al. 2018. Disentangling the molecular determinants for Cenp‐F localization to nuclear pores and kinetochores. EMBO Reports, e44742.
29618633Platani, M., et al. 2018. Seh1 targets GATOR2 and Nup153 to mitotic chromosomes. Journal of Cell Science, jcs213140.
29553540Hwang, G.H., et al. 2018. Chromatin spread preparations for the analysis of mouse oocyte progression from prophase to metaphase II. Journal of Visual Experiments, 56736.
29517484Lee, C.C., et al. 2018. Sumoylation promotes optimal APC/C activation and timely anaphase. Elife, e29539.
29513658Manterola, M., et al. 2018. BRDT is an essential epigenetic regulator for proper chromatin organization, silencing of sex chromosomes and crossover formation in male meiosis. PLOS Genetics, e1007209.
29443055Wellard, S.R., et al. 2018. A seminiferous tubule squash technique for the cytological analysis of spermatogenesis using the mouse model. Journal of Visual Experiments, 56453.
29423085Hanson, K., et al. 2018. The anti-rheumatic drug, leflunomide, synergizes with MEK inhibition to suppress melanoma growth. Oncotarget, 3815-3829.
29337080Biswas, U., et al. 2018. SMC1α substitutes for many meiotic functions of SMC1β but cannot protect telomeres from damage. Current Biology, 249-261.
28598437Guo, L.Y., et al. 2017. Centromeres are maintained by fastening CENP-A to DNA and directing an arginine anchor-dependent nucleosome transition. Nature Communications, 15775.
28539402Shirnekhi, H.K., et al. 2017. Spindle assembly checkpoint signaling and sister chromatid cohesion are disrupted by HPV E6-mediated transformation. Molecular Biology Of The Cell, 2035-2041.
28469279Magescas, J., et al. 2017. Spindle pole cohesion requires glycosylation-mediated localization of NuMA. Scientific Reports, 1474.
28272472Sgourdou, P., et al. 2017. Disruptions in asymmetric centrosome inheritance and WDR62-Aurora kinase B interactions in primary microcephaly. Scientific Reports, 43708.
28263958Chia, G., et al. 2017. Genomic instability during reprogramming by nuclear transfer is DNA replication dependent. Nature Cell Biology, 282-291.
28252645Thole, T.M., et al. 2017. Neuroblastoma cells depend on HDAC11 for mitotic cell cycle progression and survival. Cell Death and Disease, e2635.
28186092Shumilov, A., et al. 2017. Epstein–Barr virus particles induce centrosome amplification and chromosomal instability. Nature Communications, 14257.
28074901Hu, H., et al. 2017. Live visualization of genomic loci with BiFC-TALE. Scientific Reports, 40192.
28050734Jordan, P.W., et al. 2017. Sororin is enriched at the central region of synapsed meiotic chromosomes. Chromosome Research, 115-128.
27918550Ly, P., et al. 2017. Selective Y centromere inactivation triggers chromosome shattering in micronuclei and repair by non-homologous end joining. Nature Cell Biology, 68-75.
27614293Hamdane, N., et al. 2017. Disruption of the UBF gene induces aberrant somatic nucleolar bodies and disrupts embryo nucleolar precursor bodies. Gene, 5-11.

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