Immunolabeling of spreaded WT mouse pachytene spermatocytes positively labeling CREST/Centromere Protein (red, Cat 15-235, 1:20) and SYCP3 (green). Image kindly provided by Fernando Sánchez Sáez and Alberto M. Penás from Universidad de Salamanca, Spain.
Anti-Centromere Protein Antibody
Bulk Order Anti-Centromere Protein Antibody
Purified IgG derived from Human anti-Centromere positive serum (also known as CREST patient serum). Centromere refers to the DNA region where the kinetochore complex assembles, though these terms are often used interchangeably. Anti-Centromere Antibodies (derived from human CREST patient serum) are useful as controls in ANA diagnostics and also reacts with other species including mouse, rat, and hamster.
Lot dependent (1-2mg/mL)
Hamster, Human, Mouse, Rat
Serum obtained from an autoimmune patient was purified by protein A chromatography and then tested at a series of dilutions by immunocytochemistry on ethanol-fixed Hep2 cells that were in log-phase growth. The staining pattern obtained was consistent with the pattern expected for anti-centromere staining.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
24 months from opening
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