Anti-Beta-Tubulin 3 Antibody

Three different antipeptide antibodies were generated in chickens against sequences shared between the rat (AAM28438) and human (AAL28094) gene products. Antibodies were affinity-purified and mixed in equal concentration. These antibodies have been validated with human, mouse and rat tissues.

Primary Antibody
Human, Mouse, Rat
Affinity-Purified IgY
50 kDa

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Anti-Beta-Tubulin 3 Antibody

Volume: 1000 µL
Sale price$440

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Product Specific References for Applications and Species

Immunocytochemistry: Human
PMID Dilution Publication
317434431:500Candelario, K.M., et al. 2020. Exosome/microvesicle content is altered in leucine-rich repeat kinase 2 mutant induced pluripotent stem cell-derived neural cells. Journal of Comparative Neurology, 1203-1215.
311341921:2000Kamande, J.W., et al. 2019. Multi-compartment Microfluidic Device Geometry and Covalently Bound Poly-D-Lysine Influence Neuronal Maturation. Frontiers in Bioengineering and Biotechnology, 84.
304306561:1000Göttle, P., et al. 2018. Rescuing the negative impact of human endogenous retrovirus envelope protein on oligodendroglial differentiation and myelination. Glia, 160-170.
28966121not listedWang, C., et al. 2017. Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening. Stem Cell Reports, 1221-1233.
283775851:2000Bigler, R.L., et al. 2017. Messenger RNAs localized to distal projections of human stem cell derived neurons. Nature Scientific Reports, 611.
Immunocytochemistry: Mouse
PMID Dilution Publication
361504621:250Casagrande, L., et al. 2022. Moderate intestinal immunopathology after acute oral infection with Toxoplasma gondii oocysts is associated with expressive levels of serotonin. Life sciences, 120985.
356182051:250Libner, C.D., et al. 2022. Autoimmunity to a ribonucleoprotein drives neuron loss in multiple sclerosis models. Neurobiology of disease, 105775.
346970741:500Anees, A., et al. 2021. Knock-Down of Heterogeneous Nuclear Ribonucleoprotein A1 Results in Neurite Damage, Altered Stress Granule Biology, and Cellular Toxicity in Differentiated Neuronal Cells. eNeuro, .
34679349not listedLi, M., et al. 2021. Pro-Inflammatory Cytokines and Antibodies Induce hnRNP A1 Dysfunction in Mouse Primary Cortical Neurons. Brain Sciences, 1282.
322734841:200Bott, C.J., et al. 2020. Nestin Selectively Facilitates the Phosphorylation of the Lissencephaly-Linked Protein Doublecortin (DCX) by cdk5/p35 to Regulate Growth Cone Morphology and Sema3a Sensitivity in Developing Neurons. Journal of Neuroscience, 3720-3740.
308405381:200Bott, C.J., et al. 2019. Nestin in immature embryonic neurons affects axon growth cone morphology and Semaphorin3a sensitivity.. Molecular Biology of the Cell, 1214-1229.
301858851:1000Brudvig, J.J., et al. 2018. MARCKS regulates neuritogenesis and interacts with a CDC42 signaling network. Scientific Reports, 13278.
296664441:500Liu, Z., et al. 2018. Aligned contiguous microfiber platform enhances neural differentiation of embryonic stem cells. Scientific Reports, 6087.
292091581:300Al-Gharaibeh, A., et al. 2017. Induced Pluripotent Stem Cell-Derived Neural Stem Cell Transplantations Reduced Behavioral Deficits and Ameliorated Neuropathological Changes in YAC128 Mouse Model of Huntington''s Disease. Frontiers in Neuroscience, 628.
Immunocytochemistry: Rat
PMID Dilution Publication
295347521:1000Göttle, P., et al. 2018. Teriflunomide promotes oligodendroglial differentiation and myelination. Journal of Neuroinflammation, 76.
29309895not listedMuñoz, Y., et al. 2018. Reactive oxygen species released from astrocytes treated with amyloid beta oligomers elicit neuronal calcium signals that decrease phospho-Ser727-. Free Radical Biology and Medicine, 132-144.
289318111:2000Nagendran, T., et al. 2017. Distal axotomy enhances retrograde presynaptic excitability onto injured pyramidal neurons via trans-synaptic signaling. Natrue Communications, 625.
28669529not listedNagai, T., et al. 2017. Development of an in situ evaluation system for neural cells using extracellular matrix-modeled gel culture. Journal of Bioscience and Bioengineering, 430-438.
261327381:200Daadi, M.M., et al. 2016. Optogenetic Stimulation of Neural Grafts Enhances Neurotransmission and Downregulates the Inflammatory Response in Experimental Stroke Model. Cell Transplantation, 1371-1380.
256096101:1000Göttle, P., et al. 2015. Oligodendroglial Maturation Is Dependent on Intracellular Protein Shuttling. The Journal of Neuroscince, 906-919.
Immunohistochemistry: Human
PMID Dilution Publication
363030711:1000Oh, Y.M., et al. 2022. Age-related Huntington's Disease Progression Modeled in Directly Reprogrammed Patient-derived Striatal Neurons Highlights Impaired Autophagy. Nature Neuroscience, 1420-1433.
Immunohistochemistry: Mouse
PMID Dilution Publication
36370710not listedWang, X., et al. 2022. Driving Axon Regeneration By Orchestrating Neuronal And Non-Neuronal Innate Immune Responses Via The IFNγ-cGAS-STING Axis. Neuron, .
347782721:1000Hu, Z., et al. 2021. Generation of a Spiral Ganglion Neuron Degeneration Mouse Model. Frontiers in Cell and Developmental Biology, 761847.
326418261:200Muller, P.A., et al. 2020. Microbiota modulate sympathetic neurons via a gut-brain circuit. Nature, 441-446.
308204591:1000Dong, J., et al. 2019. A neuronal molecular switch through cell-cell contact that regulates quiescent neural stem cells. Science Advances, eaav4416.
300045761:1000Yamada, S., et al. 2018. Expression profile of the STAND protein Nwd1 in the developing and mature mouse central nervous system. Journal of Comparative Neurology, 2099-2114.
29463313not listedXiao, X., et al. 2018. Lymphotoxin β receptor-mediated NFκB signaling promotes glial lineage differentiation and inhibits neuronal lineage differentiation in mouse brain neural stem/progenitor cells. Journal of Neuroinflammation, 49.
Western Blot: Human
PMID Dilution Publication
297402751:1000DeVos, S.L., et al. 2018. Synaptic Tau Seeding Precedes Tau Pathology in Human Alzheimer''s Disease Brain. Frontiers in Neuroscience, 267.
Western Blot: Mouse
PMID Dilution Publication
32811565Not listedBennett, R.E., et al. 2020. Tau reduction in aged mice does not impact Microangiopathy. Acta Neuropathologica Communications, 137.
29617675not listedMorton, M.C., et al. 2018. Neonatal Subventricular Zone Neural Stem Cells Release Extracellular Vesicles that Act as a Microglial Morphogen. Cell Reports, 78-89.
27871935not listedVuong, T.A., et al. 2016. A Sonic hedgehog coreceptor, BOC regulates neuronal differentiation and neurite outgrowth via interaction with ABL and JNK activation. Cellular Signalling, 30-40.
Western Blot: Rat
PMID Dilution Publication
354742771:250Yap, C.C., et al. 2022. Dynein Is Required for Rab7-Dependent Endosome Maturation, Retrograde Dendritic Transport, and Degradation. The Journal of neuroscience : the official journal of the Society for Neuroscience, 4415-4434.
307593531:5000Cury, D.P., et al. 2019. Application of a Purified Protein From Natural Latex and the Influence of Suture Type on Achilles Tendon Repair in Rats. The American Journal of Sports Medicine, 901-914.
305878521:50000Anderson, E.M., et al. 2019. Knockdown of the histone di-methyltransferase G9a in nucleus accumbens shell decreases cocaine self-administration, stress-induced reinstatement, and anxiety.. Neuropsychopharmacology, 1370-1376.
299076581:7500Yap, C.C., et al. 2018. Degradation of dendritic cargos requires Rab7- dependent transport to somatic lysosomes. The Journal of Cell Biology, 3141-3159.
29217682not listedAnderson, E.M., et al. 2018. Overexpression of the Histone Dimethyltransferase G9a in Nucleus Accumbens Shell Increases Cocaine Self-Administration, Stress-Induced Reinstatement, and Anxiety. The Journal of Neuroscince, 803-813.
288746791:7500Yap, C.C., et al. 2017. The endosomal neuronal proteins Nsg1/NEEP21 and Nsg2/P19 are itinerant, not resident proteins of dendritic endosomes. Scientific Reports, 10481.
Additional Publications: Unspecified
PMID Publication
36310215Gribaudo, S., et al. 2009. Propagation of Distinct α-Synuclein Strains Within Human Reconstructed Neuronal Network and Associated Neuronal Dysfunctions. Methods in Molecular Biology, 357-378.

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