Anti-Ataxin-1, 11NQ Antibody (N76/3)

from NeuroMab Datasheet KO Validated KO Validated
9 Citations

Available Conjugates

490
550
594
650

Primary Antibody
Drosophila, Human, Mouse, Rat
N76/3
ICC, IHC, IP, WB
Mouse
Purified by Protein A chromatography
Atxn1 Sca1
85 kDa

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Adult rat hippocampus immunohistochemistry.
Transfected cell immunoblot: COS cells transiently transfected with Kv2.1 and Ataxin-1 plasmids and probed with N76/3 (left panel) and K89/34 (right panel) TC supe.
Adult rat cerebellum immunohistochemistry.
Adult mouse brain immunoblot: extracts of cerebella from Ataxin-1 KO and WT mice and probed with N76/3 TC supe. Image courtesy of Drs Paymaan Jafad-Nejad and Huda Zoghbi, Baylor College of Medicine.
Adult rat hippocampus immunohistochemistry.
Adult rat hippocampus immunohistochemistry.
Transfected cell immunoblot: COS cells transiently transfected with Kv2.1 and Ataxin-1 plasmids and probed with N76/3 (left panel) and K89/34 (right panel) TC supe.
Adult rat cerebellum immunohistochemistry.
Adult mouse brain immunoblot: extracts of cerebella from Ataxin-1 KO and WT mice and probed with N76/3 TC supe. Image courtesy of Drs Paymaan Jafad-Nejad and Huda Zoghbi, Baylor College of Medicine.

Anti-Ataxin-1, 11NQ Antibody
SKU: 75-122

Volume: 100 µL
1-2 business days
Price:
$308

Bulk Order Anti-Ataxin-1, 11NQ Antibody

Product Specific References for Applications and Species

Immunohistochemistry: Mouse
PMID Dilution Publication
306492331:1000Hu, Y.S., et al. 2019. Self-assembling vascular endothelial growth factor nanoparticles improve function in spinocerebellar ataxia type 1. Brain, 312-321.
Immunoprecipitation: Drosophila
PMID Dilution Publication
368484921:50Sousa, A., et al. 2023. On the Identification of Potential Novel Therapeutic Targets for Spinocerebellar Ataxia Type 1 (SCA1) Neurodegenerative Disease Using EvoPPI3. Journal of Integrative Bioinformatics, .
Western Blot: Drosophila
PMID Dilution Publication
23719381not listedPark, J., et al. 2013. RAS-MAPK-MSK1 pathway modulates ataxin 1 protein levels and toxicity in SCA1.. Nature, 325-331.
Western Blot: Human
PMID Dilution Publication
237605021:2000Bergeron, D., et al. 2013. An out-of-frame overlapping reading frame in the ataxin-1 coding sequence encodes a novel ataxin-1 interacting protein.. The Journal of Biological Chemistry, 21824-21835.
Western Blot: Mouse
PMID Dilution Publication
29533923not listedEdamakanti, C.R., et al. 2018. Mutant ataxin1 disrupts cerebellar development in spinocerebellar ataxia type 1.. The Journal of clinical investigation, 2252-2265.
27306906not listedCvetanovic, M., et al. 2017. Mutant ataxin-1 inhibits neural progenitor cell proliferation in SCA1.. The Cerebellum, 340-347.
24594842not listedVenkatraman, A., et al. 2014. The histone deacetylase HDAC3 is essential for Purkinje cell function, potentially complicating the use of HDAC inhibitors in SCA1.. Human Molecular Genetics, 3733-3745.
200977581:1000Zhang, C., et al. 2010. Loss of function of ATXN1 increases amyloid beta-protein levels by potentiating beta-secretase processing of beta-amyloid precursor protein.. The Journal of Biological Chemistry, 8515-8526.

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